MmuEX1018709 @ mm10
Exon Skipping
Gene
ENSMUSG00000027878 | Notch2
Description
notch 2 [Source:MGI Symbol;Acc:MGI:97364]
Coordinates
chr3:98107047-98111742:+
Coord C1 exon
chr3:98107047-98107157
Coord A exon
chr3:98107309-98107485
Coord C2 exon
chr3:98111550-98111742
Length
177 bp
Sequences
Splice sites
3' ss Seq
TACTTCTCTTTCTGTTCCAGACC
3' ss Score
10.9
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
Exon sequences
Seq C1 exon
GCCTTAATTGTGAAATTAATTTTGATGACTGTGCCAGCAACCCTTGTATGCACGGAGTCTGTGTGGACGGCATCAATCGCTACAGCTGTGTGTGCTCTCCGGGATTCACAG
Seq A exon
ACCTTCCTAAGTGGAAACACAGCCTTTCCTTTAGCGTTTCAGGCCACGCGTGTCTTGCTCCCTGAGACTTCCTAGCAGATGGTAACTTTCCATCCCCGTGCTTGGGTTAATGCCTGCAAAGCCACCTTTGCTTCCCCACAGGCAGAGGCCAGTGCCTTCTGTAAGGCTGTGTCCAAG
Seq C2 exon
GCCAGAGGTGCAATATTGACATTGATGAGTGTGCCTCCAACCCCTGTCGCAAGGGTGCGACGTGCATCAATGATGTGAATGGTTTCCGGTGTATATGCCCCGAGGGACCGCATCATCCTAGCTGCTACTCACAGGTGAACGAGTGCCTGAGCAATCCCTGCATCCACGGAAACTGTACTGGAGGTCTCAGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027878_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(5.3=5.3),PF0000822=EGF=PU(90.0=71.1)
A:
PF0000822=EGF=PD(3.4=4.5)
C2:
PF0000822=EGF=PD(6.7=3.1),PF0764510=EGF_CA=WD(100=55.4),PF0000822=EGF=PU(53.3=24.6)
Main Inclusion Isoform:
ENSMUST00000079812fB13719
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTGCCAGCAACCCTTGTAT
R:
GTTTCCGTGGATGCAGGGATT
Band lengths:
256-433
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types