MmuEX1022092 @ mm10
Exon Skipping
Gene
ENSMUSG00000049044 | Rapgef4
Description
Rap guanine nucleotide exchange factor (GEF) 4 [Source:MGI Symbol;Acc:MGI:1917723]
Coordinates
chr2:72141153-72174908:+
Coord C1 exon
chr2:72141153-72141172
Coord A exon
chr2:72148799-72149030
Coord C2 exon
chr2:72174802-72174908
Length
232 bp
Sequences
Splice sites
3' ss Seq
GCCCTCATCATTTGGCTCAGACA
3' ss Score
3.3
5' ss Seq
AGGGTATGT
5' ss Score
8.34
Exon sequences
Seq C1 exon
GGATTCCTGACAAGGAGAAT
Seq A exon
ACAGGAAAAAGGGAAAAAATCCCAAGTCACACCAAGTGCTGTAACTTGATAGCCTGATCCCAAAGCAAGTGAGGAAACCACACCCAAGCCTTTCCCCAGCTAACCGCAAAGATGGACCAGAATAGAGAAGGAAAGCAGGAACTTTAAGAAAACCTGGAGAAGGCTTGCGTGGGGCACAGCAAGAACTATGGATGCTATCAGAGCACTTCCCTCTGGACCTTCTAGCTTTAGG
Seq C2 exon
GTCCCTTCAGAGAAGATCCTCAGAGCTGGAAAAATTTTACGAATTGCCATTCTCTCTCGAGCTCCCCACATGATAAGAGACAGAAAGTACCACCTAAAGACATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049044_MULTIEX1-1/3=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.857 A=0.333 C2=0.006
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0061016=DEP=PU(19.7=38.9)
Main Inclusion Isoform:
ENSMUST00000090826fB15657
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types