Special

MmuEX0038798 @ mm10

Exon Skipping

Gene
Description
Rap guanine nucleotide exchange factor (GEF) 4 [Source:MGI Symbol;Acc:MGI:1917723]
Coordinates
chr2:72141153-72174908:+
Coord C1 exon
chr2:72141153-72141172
Coord A exon
chr2:72174423-72174476
Coord C2 exon
chr2:72174802-72174908
Length
54 bp
Sequences
Splice sites
3' ss Seq
TTTAACATTTTATTTTTCAGACA
3' ss Score
9.92
5' ss Seq
AAGGTAATG
5' ss Score
8.99
Exon sequences
Seq C1 exon
GGATTCCTGACAAGGAGAAT
Seq A exon
ACACCTCTCATTGAACCCCACGTTCCTCTCCGTCCTGCTCACACCATTACCAAG
Seq C2 exon
GTCCCTTCAGAGAAGATCCTCAGAGCTGGAAAAATTTTACGAATTGCCATTCTCTCTCGAGCTCCCCACATGATAAGAGACAGAAAGTACCACCTAAAGACATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049044-'27-22,'27-21,47-22
Average complexity
C1
Mappability confidence:
96%=96=100%
Protein Impact

Alternative protein isoforms (Ref)

Show PDB structure
Features
Disorder rate (Iupred):
  C1=0.857 A=0.329 C2=0.006
Domain overlap (PFAM):

C1:
NO
A:
NO
C2:
PF0061016=DEP=PU(19.7=38.9)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
Inclusion reduces interaction with RRAS2. By LUMIER.


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types