Special

MmuEX6021315 @ mm10

Exon Skipping

Description
argininosuccinate lyase [Source:MGI Symbol;Acc:MGI:88084]
Coordinates
chr5:130014679-130016373:-
Coord C1 exon
chr5:130016296-130016373
Coord A exon
chr5:130016097-130016174
Coord C2 exon
chr5:130014679-130014731
Length
78 bp
Sequences
Splice sites
3' ss Seq
CTATTCCCTATTTCCCACAGCCA
3' ss Score
8.48
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
Exon sequences
Seq C1 exon
GGAACGTGATGTCCTCTTCCCAGGGTACACACACTTGCAGAGAGCTCAGCCCATTCGCTGGAGCCACTGGATCCTGAG
Seq A exon
CCACGCTGTTGCGCTGACACGAGATTCAGAGAGACTCTTGGAGGTGCAGAAGCGGATCAATGTCTTGCCACTGGGGAG
Seq C2 exon
TGGGGCCATTGCAGGCAACCCTCTGGGTGTGGACCGGGAGCTACTCCGTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000025533-'18-26,'18-23,19-26=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.003
Domain overlap (PFAM):

C1:
PF0020615=Lyase_1=FE(10.3=100)
A:
PF0020615=Lyase_1=FE(10.3=100)
C2:
PF0020615=Lyase_1=PU(13.0=93.3)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
HIGH PSI
(asl)
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGATGTCCTCTTCCCAGGGT
R:
GAGTAGCTCCCGGTCCACAC
Band lengths:
119-197
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types