MmuEX6049375 @ mm10
Exon Skipping
Gene
ENSMUSG00000000290 | Itgb2
Description
integrin beta 2 [Source:MGI Symbol;Acc:MGI:96611]
Coordinates
chr10:77559479-77561215:+
Coord C1 exon
chr10:77559479-77559723
Coord A exon
chr10:77560150-77560291
Coord C2 exon
chr10:77561013-77561215
Length
142 bp
Sequences
Splice sites
3' ss Seq
TATCCTCTGTTGTTTTCCAGATC
3' ss Score
12.25
5' ss Seq
CAGGTGCAT
5' ss Score
4.89
Exon sequences
Seq C1 exon
GTGTGAGTCTGGCTACATTGGGAAAAACTGTGAGTGCCAGACTCAGGGTCGGAGCAGCCAGGAGCTGGAGAGAAACTGTCGGAAGGACAATAGTTCCATCGTGTGCTCAGGGCTTGGGGACTGCATCTGTGGGCAGTGTGTATGCCATACCAGTGACGTCCCCAACAAAGAGATCTTTGGGCAATACTGCGAGTGTGACAATGTCAACTGTGAGAGATATAACAGCCAAGTCTGCGGTGGCTCAG
Seq A exon
ATCGGGGTTCCTGCAACTGTGGCAAATGTAGTTGCAAGCCCGGTTACGAGGGCTCGGCCTGCCAGTGTCAGAGGTCCACCACGGGCTGTCTGAATGCACGGCTGGTAGAGTGCAGTGGCCGTGGCCACTGCCAATGCAACAG
Seq C2 exon
CTCTTGTGCCGAGTGCCTGAAGTTTGATAAGGGCCCTTTTGAGAAGAACTGTAGTGTTCAGTGTGCTGGTATGACGCTGCAGACTATCCCTTTGAAGAAAAAGCCCTGCAAGGAGAGGGACTCGGAAGGCTGTTGGATAACTTACACTTTGCAGCAGAAGGACGGAAGGAACATTTACAACATCCATGTGGAGGACAGTCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000000290-'31-24,'31-23,32-24
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PD(76.9=12.0),PF079748=EGF_2=PU(36.4=14.5)
A:
PF079748=EGF_2=PD(60.6=26.7),PF079748=EGF_2=WD(100=41.3),PF079657=Integrin_B_tail=PU(6.2=6.7)
C2:
PF079657=Integrin_B_tail=FE(85.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGCAGTGTGTATGCCATACC
R:
CCTTCCGAGTCCCTCTCCTTG
Band lengths:
244-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types