MmuEX6081849 @ mm10
Exon Skipping
Gene
ENSMUSG00000015143 | Actn1
Description
actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:2137706]
Coordinates
chr12:80177188-80181508:-
Coord C1 exon
chr12:80181361-80181508
Coord A exon
chr12:80178302-80178452
Coord C2 exon
chr12:80177188-80177296
Length
151 bp
Sequences
Splice sites
3' ss Seq
CCCCCACCCCCCCCCCCCAGGCA
3' ss Score
10.72
5' ss Seq
TAAGTACGC
5' ss Score
3.13
Exon sequences
Seq C1 exon
GATATCAACAATGCCTGGGGCTGCCTGGAACAGGCCGAGAAGGGCTACGAGGAGTGGCTGCTGAATGAGATCCGGAGGCTAGAGAGGTTGGACCACCTGGCAGAGAAGTTCCGGCAGAAGGCCTCCATCCATGAAGCCTGGACGGATG
Seq A exon
GCAAAGAAGCCATGCTTCGGCAGAAGGATTATGAGACAGCCACCCTGTCCGAGATCAAGGCCTTGCTCAAGAAGCACGAGGCTTTTGAGAGTGATCTGGCTGCCCACCAGGACCGCGTGGAGCAGATTGCGGCCATTGCCCAGGAGCTTAA
Seq C2 exon
TGAGCTGGACTACTATGACTCGCCAAGTGTCAACGCTCGTTGCCAAAAGATCTGTGACCAGTGGGACAATCTAGGGGCTCTCACTCAGAAGCGGAGGGAAGCTTTAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015143-'68-24,'68-22,70-24
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.009 C2=0.000
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(18.9=42.0),PF0043516=Spectrin=PU(17.0=36.0)
A:
PF0043516=Spectrin=FE(47.2=100)
C2:
PF0043516=Spectrin=FE(34.0=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGGGCTGCCTGGAACA
R:
TCTAAAGCTTCCCTCCGCTTCT
Band lengths:
242-393
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types