Special

MmuEX6086277 @ mm10

Exon Skipping

Gene
Description
myosin, heavy polypeptide 1, skeletal muscle, adult [Source:MGI Symbol;Acc:MGI:1339711]
Coordinates
chr11:67222147-67224575:+
Coord C1 exon
chr11:67222147-67222251
Coord A exon
chr11:67222371-67222466
Coord C2 exon
chr11:67224317-67224575
Length
96 bp
Sequences
Splice sites
3' ss Seq
ACACTTTAAAAATCTTTCAGACT
3' ss Score
6.51
5' ss Seq
GCGGTGAGA
5' ss Score
7.4
Exon sequences
Seq C1 exon
GTCCGTGAACTTGAAGGAGAAGTGGAAAATGAACAGAAGCGCAACGTGGAAGCTATCAAGGGTCTGCGCAAACATGAGAGAAGAGTGAAAGAACTCACTTATCAA
Seq A exon
ACTGAGGAAGACCGCAAGAATGTTCTCAGGCTCCAGGACCTTGTGGACAAACTGCAATCAAAGGTCAAGGCCTACAAGAGACAAGCTGAGGAAGCG
Seq C2 exon
GAGGAACAATCCAATGTCAACCTGGCCAAATTCCGCAAGATCCAGCACGAGCTGGAGGAAGCCGAGGAGCGGGCTGACATCGCGGAGTCCCAGGTCAACAAGCTGCGGGTGAAGAGCCGGGAGGTTCACACCAAAATCATAAGCGAAGAGTGATTGATCCAAGTGCAGGAAAGTGACCAAAGAGATGAGCAAAATGTGAAGATCTTTGTCACTCTGTTTTGTACTCATAACTTTGGGAGATAAAAAATTTATCTGCCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000056328-'45-42,'45-40,46-42
Average complexity
S
Mappability confidence:
67%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.743 A=0.250 C2=0.180
Domain overlap (PFAM):

C1:
PF0157614=Myosin_tail_1=FE(4.0=100)
A:
PF0157614=Myosin_tail_1=FE(3.6=100)
C2:
PF0157614=Myosin_tail_1=PD(4.7=78.4)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTCTGCGCAAACATGAGAGA
R:
ATTTTGGTGTGAACCTCCCGG
Band lengths:
182-278
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types