MmuEX6101926 @ mm9
Exon Skipping
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69304262-69307725:-
Coord C1 exon
chr2:69307430-69307725
Coord A exon
chr2:69304822-69305338
Coord C2 exon
chr2:69304262-69304414
Length
517 bp
Sequences
Splice sites
3' ss Seq
TAACTGTCTTTTGCCTGCAGGCA
3' ss Score
10.37
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GTGTGATAGGCGCAACGACTGTGGGGACTACAGTGATGAGAGGGGCTGCTCGTACCCACCCTGCCGAGATGATCAATTTACTTGTCAGAACGGGCAATGTATCACTAAGCTCTATGTCTGTGATGAGGACAATGACTGTGGAGATGGGTCGGATGAACAGGAGCACCTATGTCACACCCCAGAACCCACGTGCCCCCCTCATCAGTTCCGGTGTGACAACGGGCACTGCATCGAGATGGGGACTGTCTGTAACCATGTGGATGACTGCTCAGACAACAGTGATGAGAAAGGCTGTG
Seq A exon
GCATTAATGAGTGCCAGGATTCTTCAATCAGTCATTGTGACCACAACTGTACAGATACCATAACCAGTTTCTACTGTTCCTGTCTTCCTGGGTACAAACTCATGTCTGACAAACGTACTTGCGTGGATATTGACGAGTGCAAGGAGACACCCCAGCTCTGTAGCCAGAAGTGTGAGAATGTCATAGGCTCCTACATTTGTAAGTGTGCCCCTGGCTACATCCGTGAGCCAGATGGGAAGAGCTGCCGGCAGAATAGCAACATTGAGCCCTACCTCGTCTTCAGCAACCGTTATTATATAAGAAACTTAACTATAGATGGCACGTCATACTCTCTGATTTTGCAAGGATTGGGCAATGTTGTGGCCCTGGACTTTGATAGAGTAGAGGAGAGGCTGTATTGGATCGATGCAGAGAAACAAATTATCGAGAGGATGTTTTTGAATAAGACAAACCAGGAGACCATCATAAGCCACAGGTTAAGACGTGCTGAAAGTCTGGCTGTAGACTGGGTCAGCAG
Seq C2 exon
AAAACTCTATTGGTTGGATGCCATCCTAGATTGCCTGTTTGTCTCTGACCTTGAAGGTCGACAACGCAAAATGCTAGCCCAGCACTGTGTGGATGCAAACAATACCTTCTGTTTTGAAAATCCCAGGGGAATTGTCCTTCATCCTCAAAGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070-'58-57,'58-56,60-57=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PD(43.2=16.0),PF0005713=Ldl_recept_a=WD(100=39.0),PF0005713=Ldl_recept_a=WD(100=37.0)
A:
PF126622=cEGF=WD(100=13.9),PF146701=FXa_inhibition=WD(100=20.8),PF0005812=Ldl_recept_b=WD(100=23.7),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=94.2),PF0005812=Ldl_recept_b=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGACTGTGGGGACTACAGTGA
R:
GCATTTTGCGTTGTCGACCTT
Band lengths:
355-872
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: