MmuINT0010593 @ mm10
Intron Retention
Gene
ENSMUSG00000000532 | Acvr1b
Description
activin A receptor, type 1B [Source:MGI Symbol;Acc:MGI:1338944]
Coordinates
chr15:101193932-101195057:+
Coord C1 exon
chr15:101193932-101194171
Coord A exon
chr15:101194172-101194808
Coord C2 exon
chr15:101194809-101195057
Length
637 bp
Sequences
Splice sites
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
3' ss Seq
ATCCTTGCTCATCTTCCCAGGAC
3' ss Score
8.08
Exon sequences
Seq C1 exon
CTCTGCTGTGTGCGTGCACCAGCTGCCTACAGACCAACTACACCTGTGAGACAGATGGGGCTTGCATGGTCTCCATCTTTAACCTGGATGGCGTGGAGCACCATGTACGTACCTGCATCCCCAAGGTGGAGCTGGTTCCTGCTGGAAAGCCCTTCTACTGCCTGAGTTCAGAGGATCTGCGCAACACACACTGCTGCTATATTGACTTCTGCAACAAGATTGACCTCAGGGTCCCCAGCG
Seq A exon
GTGAGTGAGTTCTTGTGCTGTTGCCTCACCGTGGAGGAAGGGCATCTTGTCCTTTCGTTCTTGTCTGCTCTTCCCAGCCCTCAGCTCAGGGATAGCTGACAGTAGGTTTAGTTGCTCTCTGAGGTCATGACAGAGGATCAGCCTCCTTTCTAGGCAGGCTTGTTGCTCAGAAGGTGAGAAGAGCAGAGCTCCCAGCTACTTGTGGGGTCGAGGCCATCAGCAGCCGAGACATCTGCTCTGGGGACAGGGTAAACATCGTGAAGAAGGCTGAAATTTGAAAGGGAGGTGATTTCAGTGGAGCAGTGTCAGACACCACCTCAGACAGCCCCCCCCCCTTGCCATTTGTCAGATCTTTCTAGGGAAAGACTGAGAGATATTGGGCCAAGCTTGCTACTCTGGTGTGCTGTGAGCTTCCAGAGTGGGTTTGGTTCCACAGTTGTAGGGGTGCTTCACCGAGAGAAAGGTAGTATTAGAGAGAATCAAGGCACGGGCTAACCCAGGGAGACCAGAGGAAGTGGTCTCCCACAAGTGGAGACCCACAAGTGAGGGTCATTCATGGGTGGTCCAGTTACGGGGTGGGTTGGATCCAGCCGTGTCTTGTTTTCACTGTTTGTTCCATCCTTGCTCATCTTCCCAG
Seq C2 exon
GACACCTCAAGGAGCCTGCGCACCCCTCCATGTGGGGCCCTGTGGAGCTGGTCGGCATCATCGCCGGCCCCGTCTTCCTCCTCTTCCTTATCATTATCATCGTCTTCCTGGTCATCAACTATCACCAGCGTGTCTACCATAACCGCCAGAGGTTGGACATGGAGGACCCCTCTTGCGAGATGTGTCTCTCCAAAGACAAGACGCTCCAGGATCTCGTCTACGACCTCTCCACGTCAGGGTCTGGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000000532:ENSMUST00000000544:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0106418=Activin_recp=WD(100=96.3)
A:
NA
C2:
PF085157=TGF_beta_GS=PU(58.6=20.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTACGTACCTGCATCCCCA
R:
TAGACGAGATCCTGGAGCGTC
Band lengths:
358-995
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types