MmuINT0022844 @ mm10
Intron Retention
Gene
ENSMUSG00000027580 | Helz2
Description
helicase with zinc finger 2, transcriptional coactivator [Source:MGI Symbol;Acc:MGI:2385169]
Coordinates
chr2:181235752-181237997:-
Coord C1 exon
chr2:181237356-181237997
Coord A exon
chr2:181236536-181237355
Coord C2 exon
chr2:181235752-181236535
Length
820 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
GTGCCTCCCCCTTCCTACAGTGC
3' ss Score
10.65
Exon sequences
Seq C1 exon
GCTGGCCATGAAGGGCCAGGTATCCCTGAAGACAGCACTGGAGACACCAGCACTCGGCATGCTCTTCGCACCACCAGGGGCCCTCTATGCCAAGGTCCCCTTCCACTCCTCTCTGTTGCCAGACACTGATCAGGGCTTCCTGTTGAGCCGAGCAGTCAGCACAGCCCTTGTGGCTCCCGTGCCTGCGCCTAACAGTACAGTATACCAAGTGCGGCTGGAGGCACGGGCCAGTTCAGACCATGCGCTGTGGCTGCTGTTACCAGCACGATGCTGTATGGCTTTGGGGCTGCAGGCCCAAGACAGCCCCATCTTGGAGGTGCAGTTCCAGATTGACCCTATGACCTTCCGGTTCTGGCATCAGGCAGTGGATGCACTGCTCGAGGAGCACCTGGTGGTTCCTGACCTGCCTGCCTGCACCCTGCCCCACCCCTGGCCCACCCCACCCTCATTTCGTGGCAATCACAAACAGAAGCTGGCTGTGGGGCTCATTGCAGGCAGAAGACCCGAGGGCACAAAGCACATCCCACCACTGCTCATCTATGGCCCCTTTGGCACCGGCAAGACGTACACATTGGCCATGGCCGCACTTGAGGTTGTCCAGCAGCCCCACACCAAGGTGCTCATCTGCACACACACCAACAG
Seq A exon
GTGAGCCCAGAGCTGCTTCCAGGTTGCTCACCGCTGCCCTGCTTCTCAGAGCACCCATCTCTCTGATTCTTATGGAGATATGGGTTCCTTTTCCACAAACCCTAGACCAAGGAGGGAGTTATAGTAGTAATGTGTTTTGGCCTACCCTATGTTTCTTAGGCAAGGCTCTCTCTCTCTTAAATATAGAAACAGGCTATTCAACAAAGAAGTTCCTCTTTGACTAATGTGGGTTTTTTATTTATTTATATTTTAGTTCCCTAATAACACATTATTACAGGCACGGAGTCCTCTTTTAGCCCCAGAGTATGGGGTGGAAGAGCCCAGGTCAATAACCACATGTCCTGAGCTAATTTCTAGGCTGAGTTGAGGGTCTGAGTGTCAAGGCTGTTGTTGCTTATCTGAAGATCCTAGGCAGTGCTTCCTTGGCCTCTTAACTCTCAAGCTCTACTCCTGAAGATCAGACACCATTCTTGTTGCCAAAGCTTGCAGCACCCAGGAGCTGTGTTCAGGATCAGTGCCAACCCCTAGCCATGGGTGGTCTCAGGCCATAGCTATCTTTCCCCTTGGCCTCAATTAAGAGACTGCCTTCTCTAAGCTATTCCTGACCACCCATGCTCTCCAAGTCTTGCCCACTTTTCTTCAAGATCTGACCTTCCCTGTGTCTTTGCTTTTTGTCCTCTGAGGAATTTGAGTCCCTGGGCAAGACCCCTGTCTATCTGCCCTATGAGTGTTCCTGGCATCCAGGCAAGGCTGCACACATGTTTTAGCCAGCAGCCTGAGTCCTAAAGCAGCAGCCCATTGTGCCTCCCCCTTCCTACAG
Seq C2 exon
TGCTGCAGACATCTATATCCGGGAGTATTTCCACGACTACGTCAGCAGTGGCCATCCAGAGGCCACTCCACTCAGGGTGATGTATGCAGATCGTCCTCCAAGACAGACTGATCCAACCACGTTGCAGTACTGCTGCCTAACTGAGGACCGCCAGGCCTTTCGCCCACCCACAGGCCCAGAGCTGGTACATCACCGTTTAGTGGTCACCACCACTTCTCAGGCTCGTGAGCTCCAGGTGCCAGCGGGCTTCTTCTCCCACATTTTCATCGATGAGGCAGCCCAAATGCTGGAGTGTGAGGCCCTTATCCCACTCTCCTATGCCTTGTCACTAACCCGTGTAGTACTGGCAGGGGACCACATGCAGGTCACACCTAGGCTCTTCAGCGTGCCTAGGGACAAGTCAGCCAGGCACACGCTGCTGCACCGCCTCTTCCTGTACTACCAGCAGGAGGCACACAAGATCGCTCAGCAGAGTCGCATCATCTTCCATGAGAACTACCGGTCAACTGCAGCCATCATCAACTTCGTCTCCCATCATTTCTATTTAGCCAAGGGTAATCCCATCCAGGCCAGTGGCAAAGTCCCACGTCACCCCCAACACTACCCTCTCATGTTCTGCCATGTGGCAGGAAGCCCTGAGCAGGACATGTCCATGACATCCTGGCTTAACTCGGCTGAGGTCACCCAGGTGGTGGAGAAGGTGCGGGAGATCTATAACACCTGGCCTCACTGCTGGGGACCCCGGGAGCAGAGACACATCTGTGCTGTCTCTCATGGTGCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027580:ENSMUST00000121484:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.023 A=NA C2=0.069
Domain overlap (PFAM):
C1:
PF130861=AAA_11=PU(53.0=28.8)
A:
NA
C2:
PF130861=AAA_11=PD(46.2=20.6),PF130861=AAA_11=WD(100=31.7),PF130871=AAA_12=PU(61.5=48.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATGACCTTCCGGTTCTGGCA
R:
AGTCGTGGAAATACTCCCGGA
Band lengths:
344-1164
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types