MmuINT0023244 @ mm10
Intron Retention
Gene
ENSMUSG00000047228 | A2ml1
Description
alpha-2-macroglobulin like 1 [Source:MGI Symbol;Acc:MGI:3039594]
Coordinates
chr6:128561473-128566393:-
Coord C1 exon
chr6:128566244-128566393
Coord A exon
chr6:128561644-128566243
Coord C2 exon
chr6:128561473-128561643
Length
4600 bp
Sequences
Splice sites
5' ss Seq
AGCGTAAGC
5' ss Score
6.06
3' ss Seq
ATCGTACCTTCTCCTCCTAGGTG
3' ss Score
10.22
Exon sequences
Seq C1 exon
GTTAGCATAAACTTCTCACGGGATAAGGATCTACCGGGCTCTAACACCAGTGTTCATCTTCAAGCGGCCCCTGACTCCTTCTGTGCCCTGCGAGCAGTGGACAAAAGTGCCCTTCTACTGAACCACGGACAAGAAATGACACCTGAGAGC
Seq A exon
GTAAGCAGCATTGTTCCCCAGTGTCCCCAAGCTGTGTGGCTGCAAGGCCTGCCCTTCCTAGGATGCTTTTACTTGGGACGGGACATGTTGAAAGAATCAAGTCTTTACTTCTGTGCTCCTTTCTCAGTTATTAGCATGGGTTAATAACTATGTGAGTGTCTTAGTCAGGGTTTCTATTCCTGCACAAACATCATGACCAAGAAGCAAGTTGGGGAGGAAAGGGTTTATTCAGCTTACAATTCCATACTGCTGCTTATCACCAAGGAAATCAGGACTGGAACTCAAACGGGTCAGGAAGCAGGAGCTGATGCAGAGGCCATGGAGGGATGTTCTTTACTGGCTTGCCTCCCCTGGCTTGCTTAGCCTGCTCTCTTATAGAACCAAGACTACCAGCCCAGAGATGGTCCCACCCACAAGGGGCCTTTCCCCCTTGATCACTAATTGAGAAAATGCCTTACAGTTGTATCTCATGGAGGCATTTCCTCAACTGAAGCTCCTTTCTCGGTGATAACTCCAGCTGTGTCAAGTTGACAAAAAACTAGCCAGTACAGTGAGTTTTCCATCTGGCATTCACAGCAATACAGAACTCTATACATAATTATAACAAGTTAAAAACTCTGAAATAGTGTGATATTTTAAAATCGTAGTGAGAGCAGGGTTTGTTTTTTTTTAAGTTGGTCTCTATGTTCTTTGACAACGTCCAATTATGTCCTAAATATTAACTAATCTCCTGGCCCAGGATGACGCAAGCCTGACTTTACTTTCTTTGTACAGCCTTGAAAACTGATTTTGTTTTTCAGGGAACCTTGTTCCTTGAGTATGAGATATATATCTAGTTCATCTTCTTTTTAATATATATTCTCCAGTTGACATGTTACCTCTGCTCAGGTGACATGAGACACTGCCCTTATCCCGGACTGCATTTCTATTTATTCTGTTTATTTCTCTGTTTTACATTCCATTTGGTTTTTCTTTTCCAATGTCAGTCCCACAGTTTTAATGATAGAGATTAATTTTGGGTGAGATTGGACTCCTTTGGTCGGATAACTCCACCCATCTCAACTCCAGGGCACCCCTTGCTCTTCTAGTTGATTCTCAATATCCAACTTACTTCTAACTTCTCTAGCTCCAGGACAGAAAGCTAACTGGTATTTTTACTATGATTACATGAGATTTACAAATTAACTTCAATGTTTCCCCCTAATGGGGGAATATTCCAATTCAGAATTGTAAAGTGGCTTTTTTTTTCCGAGTATAATTTTTCTGTTACTCATGAATTACATCTTAAACAGTTTTCTTATGTAAACTTTATATTTGTTCACAAGTGTGTCTGAATAACTCTGTTGCTGTGGTAAACACGGTTTTTTCTCACTGTTTATTCTATTGTTATTTATGAGCCTGTCAGCTGTTTTACACAATAATTTACATTTTGCTAACTAGCTACAGTCCTTGGTTAATTAATTGACTTATATTTTTCATTGGTTCTCTATTTCCCTGTATTACAATGTTGCCATCAAATAGGAAGTTTTCTTTTTCTCACCCTCCCTCCCTGTCCCTCCTCCCTCCTTCCTCCCTCCCTTCCTCTCTCTTTCCCTTCCTTCCTCCTTTTCTTCGTTCCTTCCTCCATTCCTTCTTTCCTTCCTCCATCCCTTCCTTCCTTCCTTTCCCCTTTCATTCCTTCCTCCCTTCTTTGCTTCCTCCCTTTCTCCCTTCTTCCTTTCCTCCCTCTCTTTCTCTCCTTTCTTCCTTCCTCCCTCCCTCCCTGTCTTCTTCCCTCCTTCCTTCCTCTCTCCTTCCTTCCTTCCTTCCTTCTTCCCTTCCTCCCTTTCTTCCTTCTTCCCTTCCCCCTTTCCTTCTTTCCCCCACTTGCTTCCTTCCTTTTCATTGCACGCCTCTGTTCTCTCTTTGCCTGATTCCAGCACAGAATTACACAATGGGGACAGCAGCATCCTCACCTTGGCCTATCTTTACAAAGAGAGAAACATGAGCTTCTAGTGACTTGTGAATAACCAGCTCTGCTACATTTCTTAAGAGAATAAGATAAAATACTTTATTATTTTATGTGTATGAATGTTATCTCTGTATATACATCTATGCACACTGGAAATCGAGCCCAGGTTCTCTGGAAGAGCAGCCAATGCTCCTAACCCGCTGCTGCCTCTGGGTGCTGACATTAAAAGTCTAGGTCATCACACACAGCTTTGAAATTTTATTGTAGTGATTTTCTCGAGAATAATATAGCTTCATTTTTTTCTTGTTTAATTATGAATCCCAGCCAGTCATTCTAAGTAATAGCCAGTGACCCTAGCCAGTGACAAGCTCTTTCTCACCTTAAAGTTGATCTTTCCTTCCTTCCTTGGGAGAACACATCCTGCTTACAGCCGTGTTTCTCTATTGCTCCCTGAGCTATCCCAGTTTCCAGGTCACCTTTCAGGTACATAAATCGTATTCTCAGCTAGCTTCCTCAAAGGGCACAAGAATTCCATCACATCTTCATACTCAGAATCGTTTTTCTAAAGTCTCCACAAAGAAGCTGGGTGAACACCTGTGACATCAGCACTTGAGAGGCACAGGCAGGAGGATCAGGGGTTGAGGACCAACCTCAGCTGCATGAGACATGTTTTTTAAAAAAAACAAAACAAAACAAACAAACAAAAAACAGGGCTGGAGAGATGGCTCAGTGATTAAGAGCACTGACTGCTCTTCCAAAGGTCCTGAGTTCGATTCTCAGCAATCACATGGTGGCTCACAACCATCTGTAATGAGATCCGATGACTTCTGGTGTGTCTAAAGACAGCTACAGTGTACTCATGTACATTAAATAAATAAATATTTTAAAAAACAAACAAAGCTAACAACAAACAAAACCTTTTAAAAATAAAGAACATTGCCTTGATATGTGGGAGATGGGGTATATGACTATTAAATTTGGGGCCTGTATTTTTCTTTAGGTTTCTTGAAAACCTTGCTCTCTTGTACCTCACTGTGCTGTCAGACTAACTTATTCTCTCTGGTAGGTTATTTGGCCTCCTTGTCTGGAGGCCTAGAGGGTTTGGTTTTTATTTCCTCGAATATATTTAAACTAAAATTTTAGTAAGATATCTCTTAGGATTTATTGGGGGAAGGGGTGGAATCCGAAGCTTAGTCTGCATTGTTACTTAAAAATTAAGTTTGTTGATTTCTTCCCTTTCTTGAAAATTTTCACACATGTGTTAGCTCACTTCACAGGTGCTCAAACTCTCCAGTTTGCCTGTGGCCTACTTCCATTCTTTCTTACTTTCTCTTTTGTTTTCTATTTCTCTTCTAGAAGCTGGGTGTGCTGGGTGTGGTGATGCACATCTGTAATCTTTTTGATTTGGGAGGGAAATCAGAAGTTCAAAGCCACGATGAGCCCTTGCCTCAACAAACAAACAATGGCTGATTTCTGTCTGTCATTTTTCTCTTAGGCTTTTTAGCCTTTAGAATTCGTTTCTGATGTGTTCATCTTCTGAGTTCATTCTCAATTATTTCTTCCTTGGTTTTGCCTATTTTTATACTTTCTTTGTTACATTTCTGATTCATGATCTTTTTAAATACCTTGCATATCCATTTGCGAATATTCCCTTTATTCCAAAATATCTGAGAATTCTCTCATTGGTTGATTATTTGGACTGAGCTGTTTCAGTAATTAAAGCATGTCTTCTGTTTTATCCTGTTCCATCCTTCCCTCCCTTAAGTGCCGTGTCTCTAAGGGTTGTTGATCTTCTCTATTGACACCACTATTTCCCCCACCTGATACCCACCTGATAACCCCCACCCATGCCAGTCATGCTTTTGTGCAAATGGAAGCAGCCCCTTCATTTCAAGCCCTTCCCTCTTACTGGGAGCTAATGTGTCCCGGGAAGATGGTTCCTATTTTGACATGAGTTGTTGGAGTGTTTTTACATGGAATGAATTTGGTTTGATTTTTTTTCCTGATCCCTTCATGTCATTCTCCCTCCATGAATGTAGTTTCCTAAGCTTTCCTTCAGTTTTACATATTCTCAACTTTTCTCGCAGTTGGTCAGAACATGGTGCCCATAATTCTACCAATAACTGAAAGATTACAGGAGTCATCACTGTCTCTTCTAATCATAAAAGTATAAGTGGTTGATCTCACTCCTTGTTCACTTTTTGATTGGAGCCCATCCATTGCACGTAGCACTGGGCATCATAAGAATGGTTTCCTGTGAATATATGAAGTCCTTTGGCTGCTTGTCCGTTGCTCGATGCGATATTTTATCTGGAAGGTTTTAATTCATTAATACTTAGTTTCAGGCAGCTGACATCATTCTCCAGGCACTCCAGAAACTCTATTTCTTTACTTCAGGCAGTTATCTGTGGGCTAGGCTTTGGAACAACCAAGAGTTCTCCATGACCTTTCTTTATTTGCTATCCCCAAACCTGCACTATCGGCCAGAAAAGTTTGCATTAACATTAACTACACAAAACAATATTGGTCTCCTCATTTGAATTTTTGGAAAGTTGACTCAGTAGTAAATGGTCATGACACGAATTTTCCAATCTTATAGTTATGCAAGGAGTGCTTCACGTCACCAAGGATCGTACCTTCTCCTCCTAG
Seq C2 exon
GTGTACTTCACACTCCCGTATATCCATCAATATGGCTATTTCTACAATGGCCTCAACTTGGATGATCAGCAAGCAGAACCATGCATTCCTCAGAAGGACTTATTCTACAATGGACTGTATTATACACCTACAGGCAATATTTGGGATGGAGACCTCTCTAATCTTCTCAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000047228:ENSMUST00000060574:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF077039=A2M_N_2=PD(26.5=78.0)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types