MmuINT0026811 @ mm10
Intron Retention
Gene
ENSMUSG00000024164 | C3
Description
complement component 3 [Source:MGI Symbol;Acc:MGI:88227]
Coordinates
chr17:57225997-57226331:-
Coord C1 exon
chr17:57226166-57226331
Coord A exon
chr17:57226068-57226165
Coord C2 exon
chr17:57225997-57226067
Length
98 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGT
5' ss Score
10.65
3' ss Seq
GTCTCCCTCACATCCTCCAGTCT
3' ss Score
6.54
Exon sequences
Seq C1 exon
ATTCCAGCCAGTAAGGAATTCAACTCAGATAAGGAGGGGCACAAGTACGTGACAGTGGTGGCAAACTTCGGGGAAACGGTGGTGGAGAAAGCAGTGATGGTAAGCTTCCAGAGTGGGTACCTCTTCATCCAGACAGACAAGACCATCTACACCCCTGGCTCCACTG
Seq A exon
GTAAGTGCTGTGGGAGGCTGCTCCCACTGAGGCTGGAAGGGCCTCCCAGAGCCTAAGGTCTAAGGGGACTCTCTGTGTGTCTCCCTCACATCCTCCAG
Seq C2 exon
TCTTATATCGGATCTTCACTGTGGACAACAACCTACTGCCCGTGGGCAAGACAGTCGTCATCCTCATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024164:ENSMUST00000024988:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0183514=A2M_N=PU(16.7=28.6)
A:
NA
C2:
PF0183514=A2M_N=FE(24.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAAGGAGGGGCACAAGTACGT
R:
GGGCAGTAGGTTGTTGTCCAC
Band lengths:
178-276
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types