Special

MmuINT0040449 @ mm9

Intron Retention

Gene
ENSMUSG00000032572 | Col6a4
Description
collagen, type VI, alpha 4 [Source:MGI Symbol;Acc:MGI:1915803]
Coordinates
chr9:105979203-105982878:-
Coord C1 exon
chr9:105982276-105982878
Coord A exon
chr9:105979791-105982275
Coord C2 exon
chr9:105979203-105979790
Length
2485 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACG
5' ss Score
10.52
3' ss Seq
GTTTACCTCCTTCTTTACAGCGT
3' ss Score
9.16
Exon sequences
Seq C1 exon
TCTGCAGGGAGGCGTCTGTGGGAGACATTGTGTTTCTGGTCCACAACAGCATCAATCCCCAGCATGCCCACAGTGTGCGGAACTTCTTGTACATATTGGCAAACAGTTTGCAAGTTGGCAGAGACAACATCCGTGTGGGTCTGGCCCAGTACAGCGATACACCCACTTCTGAGTTCCTGCTTTCAGTTTATCACCGCAAAGGCGATGTGTTGAAACACATCCGTGGACTTCAGTTTAAGCCTGGAGGCAACAGGATGGGCCAGGCCCTGCAGTTCATCTTAGAGCATCACTTCCGGGAAGGAGCCGGGAGCCGGGCAAGCCAAGGGGTGCCTCAGGTGGCCGTGGTGGTGAGCAGCGGTCTAACAGAGGACCACATTCGCGAACCTGCGGAGGCTCTCAGGAGAGCGGGAATCTTGGTATACGCTATTGGGGTCAAAGACGCATCTCAGGCTGAACTCAGGGAGATTTCGAGTAGTCCCAAGGATAACTTCACCTTTTTTGTTCCCAACTTCCCTGGCTTGCCTGGCCTTGCCCAGAAGCTGCGGCCAGAGCTCTGCAGTACTCTAGGGAAGGCAGCTCAATATACTGAGCGGGAGTCTCCAG
Seq A exon
GTAACGTCTCCTTCTTTCTCATCTGGACATCAAAGAACTCCAAACTTTGTCTTTCTCACACCCCTTTACTTATTTGTGTGTGTGTGTGTGAGTGTATTTAACTCAGAGATTACAAACTCACACAACAAGATGTATCTGTTTCATTTCCCAACACTGACCACATCTCTTGCATCCTGAGGGCCTGTGGCAGTGCCATGCACTGGAAGGAGTGTAAGCCCGTTTTTGAAGGAAGGATTATTTGTTCTTAGAATGGTGTTATCATTCACGGGTTTCCCTGCCCATCTTGCCTGGCCAAGGGGCAGGGGATGAGTAGACCAGGAGGTCCCCAGGGCCTTTGCTTGCTTCATTGTCAGCATTCTGGGTCAAGAGGACACATTTTAGAGAGAAGAAAGGCCCCAGCTTAGATCCTGTCTTTCACTTCTGGTGTCATCTTGGACAAACCATTTAACCTCTCCGAATCTGAAATTTCTTCCTAGGATGACAGCACCTGTACCAGAGGGTCGGAAGCATTAGACACAGTTGTATGGTTACAAAGTTGGGCACACGGGCTACGTAACCCAGGTTACCCATGTGCACTTCCTACTGTTTTGCCCATTGGCACCTGTGAGAGGACATGCCTGTCTCTGACTTCCTTCTGCCCTTGATAGGACCCAAACTGATGAAAATCCGTCATAAGTTGGCTACTCAGCCTTACTGGAAAATACACAGCTTTGTTTTTCAAATTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTTGGTCTTTCGAGACAGGGTTTCTCTGTGTAGCCCTGGCTGTCCTGGAACTCACTTTGTAGACCAGGCTGGCCTCGAACTCAGAAATCCGCCTGCCTCTGCCTCCCGAGTGTTGGGATTAAAGGTGTGTGCCACCACGCCCGGCTTCAAATTTTTCTTAATGCATCCATTGTAGACTTGTGGACACCTGCACACGATTTCCTAAGGCATAAAACTTCAAGCAGAGAAAGAGATGACTGTACATGGTCCCATCAAACTCCACAAGAGGACAGGCCTCCATTATCTCTTTATTTTGATATTTCCCTTTAAGAGCATATAACCTGGAAGATGTGCTAAAACCTGACAGTGTGTGAGAGGTCATATACTTTAAAAATAGCACTTCAAAGTTTACAAAGATGTCTTATGTATGCAGTCATAACTACCACCAGCTTGCTGCTCTACAGCAGGGGTTCTCAGCCTTTAATACACTGCCTCATGTTGTGGTGACCCCCCCCCTTGCCCCCAACCATAAACTTTTCATTGCTATACCATAACTGTAATTTGCTACTGTTATAAATCGTAGTATAACACCTGTGTTTCCTGGCGGTGTTAATAGACCCCTGTGAAAGGGTCATTTGACCCCCCCAGAGGAGTTTTGAACCCCCAGGTTGAGAACCATGGCTCTACTTCCAGCCTTGTTTACATTTCTCATTAGGCTGGTCTATGGCCTCCAATTTGTAAATAGGCAGGATGGTTAGCATGGCTACTTTTGCATTTCTCAGATAAGGAACCTGAGGTTAATGACACCACGAGGGTGTGGTAGAGCTAGAGAGTTGTTTCCCAGGACAGTTAGACCCACTGTCTAGAGCAGGTCTGTTAGAGTGCTTGCAGAAGCAGAGCCCATGGCAAGAACTGGAATGACATACTTTAATTAGGTTTCCCTCTAAGGGGACAGTCAATAAGGCTATGCCGGACAGAGATGCAGAGGAAAGGAAGGAAGGGCCTGTGTGAACTCTGCCAAAAGTTCCACAAAGCCAGTGTTGTCCTGACCCTTTGTGGGAACCTAACAGCACATGCTCTGTGGGAACTTAAGAGCAGATGTTACGTCTCAAGGTTGTCCTGACCCTGAATTGAGGCACAACAAGAATCTGGCTTTTGTAAAATTGAGAAAAAGACAGTGGCTGGAAGGAAGTCCTCCAAAGAGCAATGCTCAGAAATGGTCAAAAGGAATCAGCAGGCCCTGAGCAGAGTCTCGATGTCTGATATAGTAGATGATCATTAAAATGCCCCTGAGCAGGTAGGGACTGTGTACAGATTTCAGCGGCAGGAGAAGAAAAGTCTCAAAGAGTGACGGACCACAGGGCTGCTAAGTGCTAGATGGGCAGTGAGACCTACTAAAGAGAATGGGATGTGTTCTAGCCAGCAAGTGCCTTGAGAGGAGGTTTTCATCACAAGATGGGGAGACAGATGGCTTATCTCGACTGGGGATAAGACCATCCCTCTTTCAGTATGCTGTTAAAATTGCAAAAGATTTACCTTCTTGCCACGAGTTTGGGGATTGTCCAGTGGGTTTTAAGGCTGGAGGCAGGAGCAGCAGCAGTCGGGCAGGCTTGAAGCCTTGGAAGATGAGTGGGGGACACCACCAGCACACCTCCGCTCTCCCTTCTTTTTGTTCAGCACCATGCTTTACCGATTCTAGGCGTTGACAGCAAACCCTCTGAGACTCGCTCTGTTTACCTCCTTCTTTACAG
Seq C2 exon
CGTGCTCAGAAGCATCCCCGGCTGACATTGTGTTTTTGGTGGACAGTTCAACTAGCATCGGACTCCAGAACTTCCAGAAAGTGAAGCATTTCCTCCACTCTGTTGTCTCGGGGCTCGACGTCAGAAGCGATCAGGTGCAAGTGGGGCTGGTCCAGTACAGTGACAACATTTACCCAGCCTTTCCGCTGAAGCAGTCCTCTCTGAAGAGCGCCGTCCTGGATCGGATCCGGAATCTGCCCTACAGCATGGGGGGCACAAGTACCGGAAGCGCCCTGGAGTTCATCAGGGCCAACTCCTTGACTGAGATGAGTGGCAGCCGTGCCAAGGATGGGGTTCCTCAGATAGTTGTCCTGGTGACAGATGGGGAGTCCAGTGATGAGGTCCAGGATGTGGCTGACCAGCTGAAAAGAGACGGGGTCTTTGTGTTTGTGGTAGGGATCAATATTCAAGATGTCCAAGAGTTGCAGAAAATAGCCAACGAGCCGTTTGAGGAGTTTCTCTTCACCACAGAAAACTTCAGCATCTTGCAGGCGCTCTCAGGAACCCTCCTTCAGGCCCTGTGTTCCACGGTGGAGAGGCAGATGAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000032572-Col6a4:NM_026763:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.015 A=NA C2=0.010
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0009223=VWA=WD(100=86.6)

							
A:
NA

							
C2:
PF0009223=VWA=WD(100=90.9)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000035186





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000112472
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr3:130563665-130564993 
LOW PSI
HsaINT0039594
(COL6A6)
Human
(hg19)
chr3:15216859-15219091 
HsaINT0039516
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
chr2:42137781-42137949 
GgaINT1001664
([1])
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"