Special

MmuINT0046470 @ mm9

Intron Retention

Gene
ENSMUSG00000026883 | Dab2ip
Description
disabled homolog 2 (Drosophila) interacting protein [Source:MGI Symbol;Acc:MGI:1916851]
Coordinates
chr2:35583578-35586514:+
Coord C1 exon
chr2:35583578-35583648
Coord A exon
chr2:35583649-35584630
Coord C2 exon
chr2:35584631-35586514
Length
982 bp
Sequences
Splice sites
5' ss Seq
GAGGTACAG
5' ss Score
6.62
3' ss Seq
GATTTTTTTTCCTTTCACAGTAT
3' ss Score
8.81
Exon sequences
Seq C1 exon
GAAAAGCGCATTGCCTCGCTGGATGCTGCCAATGCCCGCCTCATGAGTGCCCTCACACAGCTGAAAGAGAG
Seq A exon
GTACAGCATGCAAGCCCGTAACGGCGTCTCCCCCACCAACCCCACCAAATTGCAGATTACTGAGAACGGCGAGTTCAGAAACAGCAGCAATTGTTAACCTGCCTGAGGAGAGGGGGACTGTGGTGGCCCGGGACAGGGTCTCCGTCAGGAGACTCCCACAGTTGCAGGCTAGCCTGCAGTGGAGGGGGCGTAAGACTGATGGAGCGTGAGACTGAGGGCACAGTGGCCCCCCTTCTCTTTGCCCACCTGAACAGTGGGTGTGGGTAGAGGCAGCGGAGACTGCACTGGGGAGTGGGGCCAGTCTGCAGGGAGGCCTGCCGAATGTGTCTCTGGTTGTTGAGTTTGGTATGTGGCACCTTCTCTCTGAGCAGCCAGGTGCATGTACCCCTCCTTACCCTTTCCCATGGAGGAAGCTACCTGCAAAGGGCTCAAGGAAGGTTTAGGGGCCACTGCTGTGGGTTTCCCATGGCCCCCAGGACCTGATGGAGTAGTTGACAGGCAGAGTGGCCCCTGTTCATCTCTGCCCTGAGCCCCTGCCACTGCATGCAGCTGGTCAGGGACCCTTCCAGGGGGTGAGGAACTGAAGAACAGAACCTCGGTCCTATGCCCATCCCAGACGTGACACCCTCCACCCTCCTTCCCTTCCTTCCTTGCATTGCCAAACAGACAGCACTGCACTTTCTCTGCTGGGCCCTCATACCCGTGGGAGGAGCCATAGCTTCCCACACTTCACATGCGGGCCTGGCTCATGCTCTTGGAACTCCAGAAGCCAGAGAGCTGGGCAGAGGTGGCCAGGTTGCACCATGCGTTGTAGCTGCCTTCTCCAGGGTCCCAGTGTGGCCTGCACAGTGGCCCTGTGGGGAGAGGCCAGCCAGTGCTCACCCTGCAAAGGTGATCTCTCTTCTCTGATAGTTTAAGAAAGAATTCTAAAGCCTGCCGGCCCTGAGAAGGTGGATAACTGTGATTTTTTTTCCTTTCACAG
Seq C2 exon
TATGCATTAGAAACAAAAGCCCGCTTGCTCGCTTGCTGGAACACAGGGGCCTTTTAAATTGAGCGAGCGCACTGCATGGGAAATAGCGGCCCTGGAGGATGTTAGACTTGCTCCCTCTCCAAGACAGCAGCAGCCTGCACCAGGCCCCGTGTGCAGTCGCCTCTCCTCACCCTCCCAGCCCCAGCCAAGGACCCAGGCACTGCAGGCAGGGAGGGGCATCCCCCACAGCTGGGGCTGGTTTTCCCCAGCTCTAGGCTGTTCTGTAGCATATCTGTCCCTCCCCCCCCCCCCTTTGTGGGACAGAGAAGGGCAGGAGCTTGGGTCTTTCTTGGGTCCCCATCTGTTCCCACACTCTAGATTCCAAGCCCTGGTTCTGAGTCACCTAGGGCAGGAGCTAGGCTTTGCCCAGGCAGCAGAATGGGGCTAGGCAAGCTGCACTTAATGCTCCTAGAGTCCTCACTAGAAAGCGTGGACATCCTGAGGTGTGGCCTAGCTAGGCTGCGCCCTGTCCTCAGTCCACGATGGACAGGCAAGGGTAAAAGAACCCAGTTAGGCTGCAGACCAATGCTGGGAGAGGGCGTGGCTATCAAGGGTCAGAGACCTCAGGAAGGAAGGAGGTGGGGCTGAGGGCCTGCCACTGCCTCTTCCTGCCCCACTCCTGTCCACACCCCTGCTCCCATGCATTTCAGCAGGGGTGGCCTCTTGGGCAGGGCCTGGCCTGGCCTGGCCTGGCCTGGGTCTTGCCCTTCCACTGCCCAGGGAGCCCTGTTTTCCTCCTCACCCACACTCTCGCCCATGCCTCGTAAAGTGACCTCTGTCTGAGCGCCTCCTAGCAATATGGGGAGGTCCCCAGGCCTGGACAGGAGAGCGCAGGGCCAGATGCAATGGCCCCCTCTGGTGGGGTTGTTAGCTCTCAGGCCGAGAGCCTTATTTACCTAGTGCAAAAACTGTAAAAGTGTACAGACTCTCCACAGATTTTTATCTTAATTGCAAGTCTGCAATATTTTTTTTGTAAATTTTTTTTTTGTAAATGTTCTTGGTGTTTGACTGTAATGGAACTATTTCACCCAAGGGATGTACATAGTCCTTTAGTCCTGGTGCTGCGAGGGCTGGCCAGGACACTGCTCTCACGGTTGATATTAGAGCCTGGAGAACGGTGCTGGGCAGGACAAAGAGCTTTGCAGTCTAGGTGTCTGTCTGTCTGTTTCCTGCCCGGGGCATTGATTCGTTGGCTTTCAAGCATGCTGTTTGGGTGGAAGGTTGATGGGGGCAAATGCCCCAGTGGGGCCAGTAAAGCATCCTCCTGCCCACAGCAACGGCTTGGGGCGTCTGAGCTCTGCTTACAGCAAGGGCTGGAGTTGCCAGAGGCCCTGCTCTGGGAAGACCCTGGCCACTGACACCCAAGATCTGATGGAGAGAGCGGCCCCACCCTTGCCAACACAGACACCTGACCTTTTTGTTCAACTTGTGTGTTAGGGTGAAGGAAACTGCCAAACTTCCTCTGAGTGAAGACCTCTGACTGCCCAGGAGTAGGGGTGGGGACCAGGGCCAGAGCTCAACGTGTACCCCAGCACCTGCCCGAGGGACACTCCTCCCTCATACTCATAGGTCTGGGAGCCAGACTGTCCAGGGAACCAGCCCCTCTTTTCTATATACTCGGCCACAAGGCTACCCGATCCCCCACTGTGCCCAGCTCCCCCTTTTGTAAGTATGTGAAAAGGAAAAATGCAAAGGTTGGATCGGCCGGAGCCCTTCCCTCCAGTCGAGACTTTTAACCCTGTAATAATGTACAGAGAAGTTGTTGGTGTTCGAAGACTCCGTGTGGCTGTGCAATTTCTGTACATTTGCAATTAGAAATATTAAAGATTTATTTAGCTATTTTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026883-Dab2ip:NM_001114125:16
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.335 A=NA C2=0.667
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF120043=DUF3498=PD(19.5=42.9)

							
A:
NA

							
C2:
PF120043=DUF3498=PD(0.2=25.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000119058





     
                   









    
Main Skipping Isoform:
ENSMUSP00000108610





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000121506, ENSMUSP00000122341
  



Associated events







Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr9:124544681-124545814 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr11:92663938-92665085 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
chr17:9314877-9316120 
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCCCTCACACAGCTGAAAGAG

				
R: 
CCCAAGAAAGACCCAAGCTCC

				
Band lengths: 
356-1338

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"