Special

MmuINT0048826 @ mm9

Intron Retention

Gene
ENSMUSG00000038665 | Dgki
Description
diacylglycerol kinase, iota [Source:MGI Symbol;Acc:MGI:2443430]
Coordinates
chr6:36979763-36983000:-
Coord C1 exon
chr6:36982863-36983000
Coord A exon
chr6:36979842-36982862
Coord C2 exon
chr6:36979763-36979841
Length
3021 bp
Sequences
Splice sites
5' ss Seq
AAGGTTAGA
5' ss Score
6.12
3' ss Seq
AGATTTGTCCATTCTTGCAGCTT
3' ss Score
7.6
Exon sequences
Seq C1 exon
GGTTACACCGATGAGCCTGTTTCTAAGATCCTGTGCCAGGTGGAAGATGGGACCATTGTACAGTTGGATCGCTGGAACCTCCACGTAGAGAGAAACCCAGACCTGCCGCCCGAAGAACTTGAAGATGGCGTGTGTAAG
Seq A exon
GTTAGACAGCTCTTCCTTTGGGGACCGGAGTGGTGTCTTAGCTGTTAAGAGTGCTCACTGCTCCTGCAGAGGACAGGAGTTCAGTTCCTGGCACTCATATTGGCTGCTTCACAGTTATCTGGTACTCCAGCTCTAGGGAATCTGCCCCCCTCTTTTGATTTCTGTAGACCCTGGCTTATATGTGCACATACACACATATATGCATGCAAATCAATAAAAATAGAAATAAACTTAAGGTGGGGGAGACTCCTTCCACTGATGGAGCCCTGGGCATCTGCTTGAGCCGTGAGACATACATTTCAGGATACCACTCATGGGCCCTGCCTTCTAGAAGATAACAGGATAGCTCTGGGTCTCTGGCTCCTAGGGCTGAGCATACTGTCACCAGCTCCCTCTCTGAATGCTCCCTACAGAGCCTTCAGGACTCAGATATTTTACTTGTTCCAGAGCTATGGGACCTGTTCTCTGTCTTCAGCTCCACACTGGGAAAGCATATAAACATCTGTTAATCTCTTGAGCTAGATGCAGACAGTCTATGGGAAGGTGGAGTTTGTGTATGTTCCCAAGCATTAGGCAAATGGCCTTTCAGAAGGAGGAAAACCTTAGCAATTGCTGGCCTGACATCAAATATCTCTTCTGTGTAGCTGGTATCATCTAAGCCAGCTGCCTCATAGACTTGGGACTTGCCTAAATAAGTAGTCTGTCTTGGTGTTTTCTTTTGGTGACTGAGTCTTTAGGGTGAAAATTGCCCAGCCCAAATCAAGGCCATTGTTGTAAATAAACTACCGTGCAGCTTCTCCTCAGCATCTGAGCCTAAGTTGTGACCCTGGTCTCTGGTTAACTTGATTATACCACTGAGCAGGCATCCCTTCCCTGTCACGTCTTGCCTTTCTTCCATGACACCATGCCCATAATTTTGTAGGCTTAAGACTCCTTTGCTCTGCTTGTTAGAATGAACATGATGAGTCTCTCTCCAGAGAGTCAGAGTAAGTTAATGTAGGGATAAGGTCCCTGCACCTGCACTTCCAATAACATCCTTGCTAGTTTGGATCCATCCACTGAGCACAACTTCGTTGCTTACTGCAGTCCTGAGCAATTATGTTAGACACTTAGATGTCTTATTTGGCTTAAACATCTCTCTTTATATCCAGTGTTTGTTTGTTTGTTTTTTAACCTAAAGGCCAATACTGAAATTAATAAATCTTCTATTACACATCAGAATTGCTCACTTCAATTTGAGTTCACAATTGAACGTTGTTTAAACGTATGGGAAACTTTTAACTGTTCTTGTGACTGATCAAGATTGAATAGAATACCACCAAATTAGAAGGAGGGGGGGCTGTTCTACTGACATGGAAAATTTCAGGCCATTCTGCTAAATGTGGACTGGCGAGGCCTACAATTTAACTCTTTTCCCAAAAGCTTGAGAAATGGAAAGACTTCTTGATGCAGCCAGAGAACGTCAATCCAGATAATTAAAGGGCTTTGGGGATGGAGTTTGGGGATATGTAGAAAATTGGGGCACATTTTCCTGGAAAATGTGAATACCTTAAAAACAGTCTAAATTGGAATATTACTTAGGGAATTGTGTCCAGATGTTTTCTTTAGCTATCAGTGGCTGCTAAGACATGGGTTAGAATTGTAGCCAAAATAATATAAATGGTAGAATGTTTCTGTGCTTTTGGCACAAACACCATGCTATCCTTTCAGGGGCTGGGGTTTTGTTTAAGCGCAGGGACTGGACATTCTCAAATACAAAGCCAAGAGAGTTAGACATGATTTTGGCATTGGTATGTATCCTGAGTTTCTCCCTGCTCTGTAGCTTGTTGGAATTGCTTCTAAGGGCTGCTGCAGCCTCTGAAGCATCAAGATTCAGTCCGAGGGGCTTCAGTGTGGGGTCCTTTCTTCCACAAGAGACAGAAATTAAGGCAGTCTACCCCTGTCATCTATTTTAATGGGACAATGTTTTCGCTTCAACTTAGCAGGAAATCTTTCTGATCAGTAAGAAGTATACTCTAAAAAATGACTTTTGAAATGTTGAAGGTCTCAACATGCATTTCTATTAATAAAAGGGTACAATTCAGTTTGGAACATAAACCTGACAATGATCTGGAAACATTGCCTCTTTTCAGTTTAGCATTTACCTTGCATTCTAAGCCATGGAAAGAAATATGGGGTAATCATTTTATTTTCTTCCTTGCACTTTCTATGTGCTTTTCTGGTTGTTCAAGTATTGAACTAAAGCTTTTAGATGACGTCATGGGCACTTTGGCTTCATGACAATTCTTCTTGCTAGTTCACATAAAAGTCAGGGACTCAGAGCATAAAATACTAGAACTTATATATAATTGTTACGGATGTCATAGTAAAGATACAGGTTTAACCAATTAAAAGGGAATCTGAATTATACATTTTAATATTTTACACATATACAGTATATGTGATTTCATATATTATATATGGAATATATATTTCTGTTGTTTCCTGTTGGTATCAGCAGTGGCTGAATCAAATGGCACTCACTGCTTTCTTTTTTTATATGAGGTTTGTGAAAGCAAAACAAAAAAATTCCTTTAAAAATCGAGTACATGTGAATTGTTTATTTTAGGCTGCAGTATTTATGTGTTGGATATAAAGCTCTTGAAAAAACATCACACATTGATTAAGGAAATTAGACTGGATCTAGAAATCGAATTTATTTTCTAAATTCACATGGAATCAATCTCTTTATATCTGTTACAGATGAGCACCCGTCAGCTTAACAAACTTATTGCCCTATGCATAAGAATGGCTCTCACTTAGTAATTTGTATTTGTGTTCCTTATTCCTGTATAATTTGTGATTTGTGGGATCTTTTGACTTGAGCTTTCACTAATGAGTTAGTTCTAGAGCACCTGTATCTTGTCTGTAAGCACCCTTTGCAGTAGGATGTGATTTATCTGTGTCCCACACGCTGCCTCAGAGACAGGGTGTTGGGTATGGGTTGGCTGTTAATAATGACAGATTTGTCCATTCTTGCAG
Seq C2 exon
CTTCCTCTGAATGTCTTCAATAATTACTTCAGCCTTGGATTTGATGCTCACGTCACATTGGAGTTCCATGAATCCCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000038665-Dgki:NM_001081206:14
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.022 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0078119=DAGK_cat=PD(19.2=52.2)

							
A:
NA

							
C2:
PF0060914=DAGK_acc=PU(13.9=81.5)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000099071f3865A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000047858, ENSMUSP00000087788, ENSMUSP00000099071
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr7:137581929-137585208 
LOW PSI
HsaINT0047326
(DGKI)
Human
(hg19)
chr7:137266675-137269954 
LOW PSI
HsaINT0047326
(DGKI)
Rat
(rn6)
chr4:64561392-64564536 
LOW PSI
RnoINT0047015
(Dgki)
Cow
(bosTau6)
chr4:102070332-102073591 
LOW PSI
BtaINT0048628
(DGKI)
Chicken
(galGal4)
chr1:57703639-57704808 
ALTERNATIVE
GgaINT0108944
(DGKI)
Chicken
(galGal3)
chr1:59630091-59631260 
LOW PSI
GgaINT0108944
(DGKI)
Zebrafish
(danRer10)
chr7:38821063-38821179 
LOW PSI
DreINT0056539
(dgkza)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"