Special

MmuINT0057431 @ mm9

Intron Retention

Gene
ENSMUSG00000026814 | Eng
Description
endoglin [Source:MGI Symbol;Acc:MGI:95392]
Coordinates
chr2:32533443-32534092:+
Coord C1 exon
chr2:32533443-32533481
Coord A exon
chr2:32533482-32533975
Coord C2 exon
chr2:32533976-32534092
Length
494 bp
Sequences
Splice sites
5' ss Seq
CGGGTGAGA
5' ss Score
7.62
3' ss Seq
CTCCTCGTGTCCTCCCACAGAAA
3' ss Score
10.64
Exon sequences
Seq C1 exon
GTGATCATCAGTTTCCCGTCAGGCTCACCACCACTTCGG
Seq A exon
GTGAGATGGACGGTCCTACAAGGCTCTCCAACTGGTGCAGGGTGGCCTGCTGGGGTGGGGCCACTTTCTGGCCTACCAGGGAGCAGACCTCAGGAAACTCAGGCCTGAACCCTGACAAGGCCCGTGTTTCCAGTGTGCCTCAGTCTCCCCTTCCATACAATGGGAGCAGTGCTGCTGAGGGTTAAGCTTTCGGCCTCTTAAATCCAGGCAACCAGCTCACAGTGGCTGTGTCACCTTGGGCAAATCATTTAACTCTCCCCGGGGCTCAATGGTCATTGGCTATAAACTGTGGCATAAAAAAAGTCCCCACCCCATAGGGGTCTTTAAGGAGCAGTACCGAGAGGTGTGAAGTTTCTCTCCACTAGCCCAATGCCAAGTGATTTCTTCATAAATGTGAGAACTATGAGTTTATTATTTAAAAGGTGAGGATGGTGGTCAGGCGATTCCTGCTGTCACTCCGTTCAGACCGCCCGCCTCCTCGTGTCCTCCCACAG
Seq C2 exon
AAAAAGGTACAGTGCATCGACATGGACAGCCTCTCCTTCCAGCTGGGCCTCTACCTCAGCCCGCACTTCCTCCAGGCATCCAACACCATCGAACTAGGCCAGCAGGCCTTCGTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026814-Eng:NM_001146348:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.004
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0010018=Zona_pellucida=FE(14.5=100),PF0010018=Zona_pellucida=PU(3.0=30.8)

							
A:
NA

							
C2:
PF0010018=Zona_pellucida=PD(7.2=15.4),PF0010018=Zona_pellucida=FE(28.6=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000009705





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000108897, ENSMUSP00000126723, ENSMUSP00000130585
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:127818833-127819621 
ALTERNATIVE
HsaINT0056232
(ENG)
Human
(hg19)
chr9:130581112-130581900 
ALTERNATIVE
HsaINT0056232
(ENG)
Rat
(rn6)
chr3:11713077-11713548 
LOW PSI
RnoINT0054944
(Eng)
Cow
(bosTau6)
chr11:98509885-98510470 
LOW PSI
BtaINT0009071
([1])
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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