MmuINT0057766 @ mm10
Intron Retention
Gene
ENSMUSG00000055024 | Ep300
Description
E1A binding protein p300 [Source:MGI Symbol;Acc:MGI:1276116]
Coordinates
chr15:81630001-81631853:+
Coord C1 exon
chr15:81630001-81630119
Coord A exon
chr15:81630120-81631613
Coord C2 exon
chr15:81631614-81631853
Length
1494 bp
Sequences
Splice sites
5' ss Seq
CCTGTAAGT
5' ss Score
7.52
3' ss Seq
GGTGTTGCTTACACTTTTAGGAT
3' ss Score
8.01
Exon sequences
Seq C1 exon
TTTTCAAACCAGAGGAATTACGACAGGCTCTGATGCCAACATTGGAGGCACTTTACCGGCAGGACCCAGAATCTCTTCCCTTTCGTCAGCCTGTGGACCCGCAGCTTCTAGGAATCCCT
Seq A exon
GTAAGTATTTGGTATTTTTCTATTTTCTTTTAGATAGAGAAACAACTTTATTAACATGATTGCTGTTACAGAAGTTAACCTATGTACAGTGTACAAGTTTTAGCATTTTCATTGTTATATAGCTATCACCATGGTTTTAATTCATTTTCATAACCTCCCCCAATAAACCCCACGTCCATTAAAATTGCTAGTTGCAGCACTCTTACTTTCCCAGCCTTAGGACTGCCTAACTCCTGGATTCTTCTAGTTTGAATCACACTCAGTGTGGAATGAAAGCTTAGCAAGTGCTTTGCACTGACCCCTGGTCACCAGTACAGCCTTTGAGGTTCTTCCATGTTATGTGACTGTGTCACCCAGTGCTTCCTTTAAATCATTTAGTATTCAGTTATGTTGATATTACTGCATTTTGTGTATGTATTTAATTGGGAAGTTATTTGCAGTTTTGGGCTATTGAGACTATGGCTGCTGTGAAGGTCGGTGTACAAGTACTGCTTTGCCTATTATTGGTTAAGATTTTGAGAGATTCTCTCTTTATATCTCATGTTATCCTTGAACTTGTAGGTCCTGCCTTGGCCTTCATGTACTGATACTTCAGGAGTGTGTACATTTTTATGTGTTACAGATTGATTTTTCTCTCTGGTATGTTAGAGGTCAATAATTCACTATCATCTCAACAGCTATAGATCACAGCAGAAAGATGAGTCCCTTGGTTCTGAAGATTTATGTGTATGATCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGGTGTGTTGGTGTGTATTTTGGGTGCCAGGTTCCTCTGCCGAAAGAGAGTGGTAAGTCCCCATAGAAGTGGAGTTGAAGATGGTTGTGATCTATCATGTAGGTGCATAAAGCTGAACCTGTAGCCTCTATAAGAGCAGCAAATGCTTTTTAACTGCTGAGCCAGGGTCTCTTCCTCTATTTCAACCCTCAAGTTTGGGGTTTTATTTTTGTTTTGTTTTTTTTTTTGATATGAGGGTTGGGTTAGGGTGTGTATGTGTCCCTGGTTAGCCTGAGATTGACTCTGTAGACCAGACTATCTTCAAACTCATGGTCATCTACTTGCTTTCCCAAAGTTAGCTTTGAAATGTTTGAACATTGTAATGTACCCAGGTTGCTTGCTGGTTTTATAAAAGATTTTCATATGTGTTTATTTAGGATTTTTTTTCCATGTTTTTCTGTTACCTTAGAACACTGATTCTCTAGGATTTGTATGCCCTTCTAGTACTTAATCCTCAAAACCTCTTAAAAATTGGTAGATTCATATTTTAAAGAAGTGACAGACTTCAATCAACTCGTGGGACGACATATCAAGACACATAACATTATGTGGAAAATTAATGACGATAATAGGAAGACACTCCCTCTTCCCTAAATACCCTGCTCATGAGTATGTGATGTGGTGTTGCTTACACTTTTAG
Seq C2 exon
GATTACTTTGATATTGTGAAGAGCCCCATGGATCTTTCTACAATCAAGAGGAAGTTAGATACTGGACAATACCAAGAGCCCTGGCAATATATAGATGATATTTGGCTTATGTTCAACAATGCCTGGTTATATAACCGTAAAACTTCAAGGGTATACAAATATTGCTCTAAACTTTCTGAAGTATTTGAACAAGAAATTGACCCTGTCATGCAAAGCCTTGGATACTGTTGTGGCAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000055024:ENSMUST00000068387:17
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.575 A=NA C2=0.013
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PU(33.3=72.5)
A:
NA
C2:
PF0043920=Bromodomain=PD(64.4=70.0),PF060018=DUF902=PU(28.6=15.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCAGAGGAATTACGACAGGCT
R:
TGCCACAACAGTATCCAAGGC
Band lengths:
347-1841
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types