Special

MmuINT0062961 @ mm9

Intron Retention

Gene
ENSMUSG00000024598 | Fbn2
Description
fibrillin 2 [Source:MGI Symbol;Acc:MGI:95490]
Coordinates
chr18:58204923-58207704:-
Coord C1 exon
chr18:58207579-58207704
Coord A exon
chr18:58205040-58207578
Coord C2 exon
chr18:58204923-58205039
Length
2539 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGA
5' ss Score
8.91
3' ss Seq
AGCTGAGTTCTTCTTGGCAGATG
3' ss Score
5.98
Exon sequences
Seq C1 exon
ATCGCAATGAATGCTTGGAAATTCCTAATGTTTGCAGTCATGGGTTGTGTGTTGATCTGCAAGGGAGTTACCAGTGTATCTGCAACAATGGCTTTAAGGCTTCTCAAGACCAGACCATGTGCATGG
Seq A exon
GTAAGAAGGGTGTTCTGTCCCAGGGAGTGACGTGAGGCTGGGACTTAAGGGCAGATGATGGCACCACCATATGACCTCAGCAACGATGACGTCTCTGCCATGCTAAACAGTTTAAGGCTTTGATGTAAAACTGGCAAGCAGAGACAATACCATACTAGGTTCTCAAATGCTCAGCAAGTCTCAGCATTTTGCTCCAGAAGTTCCTATGAGATGATGTGCGTTCAGGCACACTTGGGGCTAGGTGGAAATCACCCACACAGCATATTTTGGAGTGCAAACGAGGAGTAAGGGTGACCCTACTAACATAAGCACCATGCAAATACACATTCTTTTTTATTGAGAATATAGCTTAGGACGTAACAGTATCAGTGTCAGCTTTAACTCTTAACATGATTGCAGAAGTGAATATAACCAGCGTCTTTAAAATGGATTCCCATCAGGCAACATAGCAGCTACATAAGGAAATGCTCACAGTCAGCTATTGGATGGATCACAGGGCCCCCAATGGAGGAGCTAGAGAAAGCACCCAAGGAGCTGGGGGGGATCTACAACCCTATAGGTGGAACAACAATATGAACTAACCAGTACCCCAGAGCTCGTGTCTCTAGCTGCATATGTATCAGAAGATGGCCTATCCGGCCATCAGTGGAAAGAGAGGCCCATTGGTCGTGCAAACTTTACATGCCTCAGTACAGGGGAACGCCAGGGCCAAAAAGTGGGAGTGGGTGGGTGGGGGAGTGGGTGTGGGAGCGTGTGGGGGACTTTTGGGATAGCATTGGAAATGTAAATGAAATAATACCTAATTTAAAAAAAATTTTTTTAATTAAAAAAAAAAAGGAAATGAGAGTGGGGCTTAGGTTGTTTACAAAGGCACATGGTAGAGGGGGGGGGGTGCTCTGAAGCGGATTGCCAGAATGTCCCAACTCTGATGTCAGTAGGGGGCTGGGCCTCTGCCAGAGTTCCTCTCTGTGCTTCATATTTGAAAGAGGAAAATTGGATTTAAAATTTGCTTATTCAGATGTAGCACGCTCTCTGTGTGGGAAGGCCAAGGCTGTGTACCCAATCTTTGGGGATTCTAGACGCTTGCTGAGTGAGTGTGAAAGCCGGGTTTCAATAGTGTGGAAGCGTTCCCTTCGTGGAGTATCTGTGCAACGAGGAGCAGCTGGGGAAAGCCTCAGTTTACCCACTGCTCCCTGAGTGCACCTTCCCACCATGGGCTGCCCCAGAGTGATGGGGAAATCTCTAACTGGCGCCTGTGCGGAGGCTATCACAAGTCCCCGTCCCCTGTCCATGCACATTGTGGGAATGCTTGCTTTTACAAGAGACACGGGGGTCTCCGTCTATGCTCTTGCAGAGAGTATAATCCGCCCTTCGTCCCCAGATCTGTGATATTTATGACCCAGAAATTCATATGGGAAAAAAAAAAAAAGCCGCCCCAGTGTTAGCAGTTCTTCCATGATAAAAGTCAGTCAGCTCCTCGGACCTCCGGGACACAGCTCTCCTTCTAAAGAGCTGTGCCTGTTCCTTGTACGGTGGCTCTCTGCAGGCTGGCCTCCCAGCTCAAAGGCCTTAAAGGGACTCTAGCCAGTCCAAGAATGACCGACCATCACAGCTCTGGCAGACCTTGTCCTTCCTGAGTCACTCTGCCTCGCTAAATAAATGAATAAATAAATAAGAGTTAGATTGCATTTCTAAAGCTACCCACCAAGGTCTGTTCCCTTATTTGGCCACATCCTCCACCTGAGACTGACTACCGAGGTCTAGCTTTCTAAGTACTGAAGTCAAGCAATCAAACGACCACTTTGAGCTGCCCTAATTAGCATTCCCAATCAAAATGAATCCTAACATGGGTTTCACCTTCAACTTTTATAAACCACCAACCACCATTGGGCCATGGCTGTCTCCTCTCCATCAAGAGGAGTCCTTTGTCCCCCTCCCAGACAAATACCCCTGTCCCCTCTCCCTCATTTTCCTTCCCCTTCTTCTTTGTTCTCTATCTCCTGTCTTTGTCCCTTATTCCACAACCTTTTTCCCTCTGGGGCACATAAGTCTCCTTTGTGCTGAGTACTTGGTTTTGGGGGTATCCTGTGCTGAAACCGATCCTTCCGGGCCCTCTGTCTCCTGTCTGGAATAAAACTGTTCATGCCAGGAATTTTGGAAAGCTTATGATTAATTCTAAATGAACTCCTTGGATTTCACTATTTCATCAAAGGGGCTAAAGTTTTCCTTCTGAAGTTAAGATATATAAATTCTTTAATAAGTGTTAAGAATATTTTGCTATTTGACAAGCAAGCCCGCTCTCTGCAACATCTCTGCCGGTGGCACGCCTCTCCGCCCTCTGTTGCTGAGAATTGTACTGACTGGTAGGGAATTAAACTGTTTTCTCCTTCGTAAATTCATAAGTTTGATTTGCGTCCCCCTTTTCACCTTCTTATTTTTATTAAGTAAGCTTGGGTCCCTAGCACTCTCCTTAGTGCGGGCAAGAAGATGTTAGAGGTGCATGCCTGGTTCTAGGTAAAAGCTGAGTTCTTCTTGGCAG
Seq C2 exon
ATGTCGACGAGTGTGAGCGGCACCCGTGCGGAAACGGGACTTGTAAGAACACTGTGGGATCCTACAACTGTCTGTGTTACCCTGGGTTCGAGCTCACTCACAACAACGATTGCCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024598-Fbn2:NM_010181:45
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF062476=Plasmod_Pvs28=PD(20.4=46.5),PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
NA

							
C2:
PF0764510=EGF_CA=WD(100=95.0),PF0764510=EGF_CA=PU(0.1=0.0)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000025497





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000058181
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr5:128303090-128304956 
LOW PSI
HsaINT0062477
(FBN2)
Human
(hg19)
chr5:127638782-127640648 
LOW PSI
HsaINT0062477
(FBN2)
Rat
(rn6)
chr18:53105119-53107642 
LOW PSI
RnoINT0059634
(Fbn2)
Cow
(bosTau6)
chr7:26883787-26886189 
LOW PSI
BtaINT0061130
(FBN2)
Chicken
(galGal4)
chrZ:56611900-56612893 
LOW PSI
GgaINT0062437
(fbn2)
Chicken
(galGal3)
chrZ:55671312-55672305 
LOW PSI
GgaINT0062437
(FBN2)
Zebrafish
(danRer10)
chr22:4092896-4092992 
LOW PSI
DreINT0010638
(FBN3)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"