MmuINT0062975 @ mm9
Intron Retention
Gene
ENSMUSG00000024598 | Fbn2
Description
fibrillin 2 [Source:MGI Symbol;Acc:MGI:95490]
Coordinates
chr18:58182827-58184805:-
Coord C1 exon
chr18:58184680-58184805
Coord A exon
chr18:58182950-58184679
Coord C2 exon
chr18:58182827-58182949
Length
1730 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAGA
5' ss Score
9.14
3' ss Seq
TTGCTCTTTCCTCTACTTAGACC
3' ss Score
8.61
Exon sequences
Seq C1 exon
ATATCGATGAATGTAAGGTGATGCCAAGCCTCTGCACTAATGGCCAGTGCGTCAACACCATGGGCTCCTTCCGGTGCTTCTGCAAAGTTGGCTACACCACGGACATCAGCGGAACAGCTTGTGTAG
Seq A exon
GTAAGATGTGGCTGTACACCCGGGGTTTGGCAACTCCTGCTGCCTACAGACCGAGCACCGTCAGGGGAGCACTGGCCTATGCCTCCTACAGACCGAGCACCTTCAGGGGAGCACTGAGCTATGCTTCCTACAGACCGAGCACTGTCAGGGGAGCACTGACCTATGCTTCCTACAGACCGAGCACATTCAGGGGAGCACAGGCCTTTTCAGCTTTCACTATGCTGACCGGAAGTCTCAGTAATGATCCTCTTAATGACAGAGATCTTGTTTGGTTTGTTTGTTTGCTTGCTTGATTGATTGCTTAACTGTGTGGGACACGGGGTCCAGGTCATCTCAGATTCTGTGCAGTGGGGGAAACATAAAAATCAAAAAAAAAATGAGTTTTCAATATGTTCATTTTAATTTAAAACTTACAAACGCATATCTATTTGGTAAAGAAAAGGAAGTGGGCTTTTCCTGTGGATCCGGTGTGTTTGTGTGTGAAGAAGAATTCATTTTTAATAATGTCTCATGAAGTGCAGCAACTAAGCATCATCTAAAAGCTCTGCTTGCAAAGAAATCTCACCAAAGCATCCTCTGGCTGTTTACATGTATTTCTCTTCTTTAATTCATAATCATCTGATCTGTGCCATTTTCTGACAAACAGAAGGCTGTGGTAGAGCCTTCTTGTACACTTTCAAACAGTTCTTATTTCTATTTCCCCGGCTTTATGAGACACCCTCTTAAATTACCAACTTTACAAAGGTTAAGCAAAACCGACCAACTCCACAAAAGCATTTTAGTCACACAGTAGAAACAGCAGACAGGGGAGTAGCCAGGAGTGGGATCCAAATCAGGAGTTTCTGCGTGCAGCAGGCCTCCGTTCATCCCGGGAGCTCTGTGGAGGAAATGGAGATTGTCTGCCATCAGTCACAGTCCTGGCAGTAAAGAGTTGGCATAGCCCAGAGAGGACAGACGAAGTATAGCTTAGCATCAAGATTGTGTCAGTCGGTGGTTCTCAACCTTCCTGATGCTGTTGCCCTTTAATAGAGCCCCTCATGTTGTGCTAACCCCCCGTGTCCTCCCCCCACCATAAAATTATTTCTCTCTATTTCCCCATAAAATTATTTTCGTTGCTACTCCATAACTGTCATTTTTATAGAGGAGCAGCATCTCAGTTTGTAAGACAGTCTGAAATGTTATTTCCCAATGGTGGCGACCATCGTAAGGTTGAGACCCGACCCGCTGCTGTAAGTGGACAGCGGGGTGTAGAGATGCCACAAAGCAGGGGTTCACCAGAGCTTATGTAACTCCACTCTGGGGCCAAACAAAAGGAACAGAGGGGAACGTGGTGAGACCCTGAGAGAACAGAGTGTGCAGAGAGCATCTGTGAGAAGCTGCCGCAGGAAGCCACTGTCTCAGCATAAACCCACGCCAGAGAGACAAGAGGAAATGGGAGTGTTCCTAAGGTCTAGTCTAGCCTGATTAAGTTGAAGAGCTTCTTGAGTTTGGATTTTTTTTTTTTTTTGAGCCTAGACAGTCGTCTAGACATTACAAGATCTAGCCAAGATCTGTGCATTGATCCTCGAAATACGCCAGTCTGCTACTTTAGAGAAAACTGTTCTTGCTGGATGAATTCACTGTATGTTGTAGAGGGAAAGCAAGAAGGACGGAGTGAGAATGTGGGGAGGATGGAGAGGCTGGTCCTTTCTGGTAACCAGGACTCTCATGTTGCTCTTTCCTCTACTTAG
Seq C2 exon
ACCTCGATGAATGTTCGCAGTCTCCAAAGCCATGCAACTTCATCTGCAAGAACACCAAGGGCAGTTACCAGTGCTCCTGCCCACGGGGGTACGTCCTGCAGGAGGACGGAAAGACGTGCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024598-Fbn2:NM_010181:58
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=95.2),PF0764510=EGF_CA=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGATGAATGTAAGGTGATGCCA
R:
CTTTGCACGTCTTTCCGTCCT
Band lengths:
246-1976
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: