MmuINT0092630 @ mm10
Intron Retention
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69453792-69454926:-
Coord C1 exon
chr2:69454810-69454926
Coord A exon
chr2:69453930-69454809
Coord C2 exon
chr2:69453792-69453929
Length
880 bp
Sequences
Splice sites
5' ss Seq
GCCGTAAGT
5' ss Score
10.11
3' ss Seq
TGTCCCCTCCTTACCAACAGCGA
3' ss Score
9.91
Exon sequences
Seq C1 exon
AGATGAAGACGTGCCATCCTGAACATTTTCAGTGTACGAGTGGACACTGTGTGCCCAAGGCGTTGGCATGCGATGGGAGAGCAGACTGTCTGGATGCTTCTGATGAGTCCGCTTGCC
Seq A exon
GTAAGTGCCTGCTCACTTGAGGTCCTGTGTGTTTCAGTGCATAGGAAGGGCAATTTAGACCCAACCCACTTCTTAGTTTAAAAGCCTAAGTATGTTCTCTTCAGCCTTCTCATGACGTTGAGTTTGCCTGAGTCATTATTTCCCAGTGGACTTAGGATCCCTAGTTGTTTGTAGTGGTCGTGCAGTAGTTATCTACAGTAGACTTTTGATGATGCAGCTGCCGCTTTCTGAAGTTCAGGGAGACAATCAAAGATGATGGGAAAGACAGTTTTGATACATGTGGTAAGTGGCGATTGGCCAGAGAGACACAGTATAGTGTTCTCTCTGTGATGATTTGTGTCACTGAAAACTGGGTTCAGAGAACTGTCTTGCCCTTAAGACATAAACACCCCCTGTCTTTTTGGTTTTCCAAGACAGGGTTTCTCTGTGTAACTGTGGTTGTCCTGGAACTCACTCTGTAGACCAGGCTGGCCTCGAACTCAGAGAACCACCTGTCACTGCCTCCCGAGTGCTAGTATTAAGTGTGCGCCACTACACCCGGCCAAAGACATTTATATCCCTTTTTATAGATAAGCCACAACAACAGGGTAATGAATAATGAAGAGTCACAATAGCAGGTGTTGAGGGAGACCCAACTTCAGGTTTCTGATGGTTGTAAACTTCGATATAGGTGCTAGGAATGGAACCTGGGTGCTCTGGAAGAGCAGCAAGAACTCTTAATCTCTGAGCCATCTCTCCAGCTCCCGATAACCACTATTTTAAAATCTCCAGAGCTTTTTGGATTCATTCCTGGTTAAGAGCTATTGATTTCCATAAAGTGAGTAAAACTGTATATGTCTATCTCATTAATGTTTTGTATGTGTCCCCTCCTTACCAACAG
Seq C2 exon
CGACTCGCTTTCCCAATGGTACCTACTGCCCAGCTGCCATGTTCGAATGTAAAAACCACGTGTGCATCCAGTCATTTTGGATATGTGATGGGGAAAATGACTGTGTCGACGGTTCTGATGAGGAGATTCACCTGTGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070:ENSMUST00000080953:60
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=92.5)
A:
NA
C2:
PF0005713=Ldl_recept_a=WD(100=83.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATGAAGACGTGCCATCCTG
R:
GCACAGGTGAATCTCCTCATCA
Band lengths:
254-1134
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types