Special

MmuINT0103217 @ mm9

Intron Retention

Gene
ENSMUSG00000020900 | Myh10
Description
myosin, heavy polypeptide 10, non-muscle [Source:MGI Symbol;Acc:MGI:1930780]
Coordinates
chr11:68581701-68584559:+
Coord C1 exon
chr11:68581701-68581874
Coord A exon
chr11:68581875-68584385
Coord C2 exon
chr11:68584386-68584559
Length
2511 bp
Sequences
Splice sites
5' ss Seq
CCTGTGAGT
5' ss Score
7.21
3' ss Seq
TCACTGCCTCTCATTCTCAGGCC
3' ss Score
9.66
Exon sequences
Seq C1 exon
CTGAACTCCTTCGAGCAGCTGTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTGTTCAACCACACCATGTTCATCCTGGAGCAGGAGGAGTACCAGCGAGAGGGCATCGAGTGGAACTTTATCGACTTCGGCCTGGACCTGCAGCCCTGCATCGACCTGATAGAGAGACCT
Seq A exon
GTGAGTGCCTCCTCCCTGCCCAGCTTCCTGCTCTGTTGAGCAGAGACTTCAGTTTTCTTTCTGGCATAATCTGAGACAGACGATCTAGAAAATGATACTCTGATAACACGATTTACTTAAAAGTGTGTGATCTGGCAGTCAGAGCCTTTGTTAGGTCTCCTCAGGTGCAGCCTTGAATCCCCTGTCCTTGTGTTTGTGCATGTGTCAGATAATGTGCTGTGGTCCTCACAGACCACAGAGACCAGTATGATGGTTGCACTGGTGTGTACCTGTCAAAGGGCGTGTGCCGCTCCACTTCCTTCCTAGGTAATACAGGGACACTTAGCTGAGAACAAAATGTGTCACATAAACTTAGTTTTTAGATAATTGAATTTGAGCTCAGCCTTTTGTAAGTATTTTTTGACAGTTTTTTGTTTTTGAAGTATGTTTGAGGAGGCATTCTTTTGGCAAATATACATTTAAGGACACACGATGTGGGATAGTCCATAGCTTAGCTCTGCCAAGATAGAGTAAGCTAGCCCTTCATGATAATTCCTGCTCCACTTACGGTCTGACATATGATTCTGGGCCAGAAGGCTGGAGACAGATGCTGGAAAGGGAGTGAGAGAATGTTCTGGGGCAGCACTGGGTGGTACAGTGGTCACCGTAACCACATATCTTAGACACTCCAGGCAGGAGGAGGTAAGCTCCTTCCGACTTCCCCTCTTGGCCTCCATGGGCACCAGCACCCATGTTCACAGACACATAAAAATAATAAAACAGATCTAGGATTTAGGAATGTTTTCATTCAAGGGGATTGGAAATTGAATGTTATAATTCCTATGACCTTAACATTAGTGGCATGCTTAATTTCTCAGACCGTTGACAGTAGCTCCAGCTACCTGCCCCTGTGATCCTGGCTCAGTAGCCCCAGCTATTTGCCTCTATGACCCTGGCTCAGTATTATTAACTCCCTTCCACTGTAACCCTAACACAGTAGCCTGCCACTGTGACCATGGTTTCTCTAGAAGTAGCTAACCTCGGACAATGTGGATTATCATCTCTCTTTAACTGATCTGACACCCCGAAAGCTCTTTGAGAAGGAACCCAGGGGTAAGGGTCTCGCTGTAGAAGGGTTCCTAGGTCCCATGAACCGTGTGCTTCATTCAGCAAGTGCCTGGATCTATCACCATCACATTGCTTCGTTTATACTCAACTGTAACCCCTGCTTGCCTTCCAGATAGCATCTTCATCCAGTAAATACCTGAGGAAAATAGTTTCTAAAGTTTTATACAAAAAGAAAAAAATTCAGAATGTGAATTCAGTGCCGTGTCACATGCTGGGGCCGCACTGGCGCTATAGCAGTAAACAATAGCCCAGAAGCACTACTAAGGAGCCTGCTGCTCTCTAAATACTTTATTTCTGTTTCCAAGTCACTTATGTAGAAAAAGAAAGTCATCGAAGAAAAGGCAAGCTGTAGATTTTTTATTATTTTTAATTAAGACATAATTCACATGCGTAAATGAATGTAAATGAACCTGTTAAGGCTGGAATTCAGCAGTTTTGTGCTATATCATACCACTAATTCTACACTGTCATGACTCCACCCCGGTAAAATCCTGATACCCGGTAGCCCCACACCCAGCATAGTGCAACTGATGTGCTTTCTGTCTCTGGATTTGCCACAGCCTTTTAAAGTGACTGATGTTTGTATTACCCCCTCTCATAATTTATTAGTCACTTTTCTGTTGTTTCGATAGAACAAAACAACTCACAGAAGGAAGGGTTTAACTTAGGCTAACAGTTCCAGAGGGAGGAGAGGCCATTGAGGTAGGTGATTGTGGCAGCCGGCAACAGTCATGGTGGCAGGAACAACTTGAGAGTGAACCAGGAATGGCGTTGTGGTTGTGTGACTTTGAAACCTCAAGAACTAAGAACTTCCTCCAACAAGGCCACGCCTCCCCCAAACATCACCACCAGCTGGGGACTGAGTATTCAAATGCCAGAGTCTGGGGACATTTTTCCTCAAACAATCACACTGTGCTGTACTGAGTAATAGCTTTAGATATTTTACCGACAAGAAGTGGTACAGCCTATTGAATCATCAGTTAAACAAAAACTTAAATGGCTTAGCATGGACAGTGTCTGCTTAGTTGAGCTTTATAGTATACCCAGCAGCCTTGACCATAGAGTGCTCACTTTGACCCCTCCACCCTTGTCCCATCCCCTCTCCCAGCTCCTTTCTGCTTCTGGATGCTTTTGTAGAGCGTCTACTGTAATTAGTTTACTTATAATGTACATACTTCAAGATTTCAAGGCTTATTCGGTAAGTTACCCATTTCTTTCCAGTGCTTAGTAACTTAATGGTCTGTGTTTGAACTTTTAGCTTGTTATGGCATGGACATACTTTCCATTGGAGAAGCTAGTTCTTTCATAGCTCTTCACAGAGTTGTTGGTTGTGGCGGTAAGCTGCCAATCCCCGAGGTGGAGCCATGACTAGCTTTGTCAGTGCTCACTGCCTCTCATTCTCAG
Seq C2 exon
GCCAATCCCCCTGGCGTGCTGGCCCTCCTGGATGAAGAATGCTGGTTCCCCAAAGCTACAGATAAAACATTTGTTGAAAAGCTGGTTCAGGAGCAAGGTTCCCACTCCAAGTTTCAGAAGCCGCGCCAACTGAAAGACAAAGCCGACTTCTGCATCATCCACTACGCGGGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020900-Myh10:NM_175260:13
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.017
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006316=Myosin_head=FE(8.0=100)

							
A:
NA

							
C2:
PF0006316=Myosin_head=FE(8.0=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000090661





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000018887, ENSMUSP00000090661f862A, ENSMUSP00000099671
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr17:8535932-8542106 
LOW PSI
HsaINT0107462
(MYH10)
Human
(hg19)
chr17:8439250-8445424 
LOW PSI
HsaINT0107462
(MYH10)
Rat
(rn6)
chr10:55359630-55361727 
LOW PSI
RnoINT0096306
(Myh10)
Cow
(bosTau6)
chr19:28721009-28723568 
ALTERNATIVE
BtaINT0097083
(MYH10)
Chicken
(galGal4)
chr18:1729602-1731248 
LOW PSI
GgaINT0127243
(MYH10)
Chicken
(galGal3)
chr18:1716629-1718275 
LOW PSI
GgaINT0127243
(Q789A6_CHICK)
Zebrafish
(danRer10)
chr6:7454808-7455118 
LOW PSI
DreINT0099723
(myh10)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"