MmuINT0109743 @ mm9
Intron Retention
Gene
ENSMUSG00000026923 | Notch1
Description
Notch gene homolog 1 (Drosophila) [Source:MGI Symbol;Acc:MGI:97363]
Coordinates
chr2:26325125-26325578:-
Coord C1 exon
chr2:26325321-26325578
Coord A exon
chr2:26325238-26325320
Coord C2 exon
chr2:26325125-26325237
Length
83 bp
Sequences
Splice sites
5' ss Seq
CTGGTGCGT
5' ss Score
8.29
3' ss Seq
ACTGTCCCTTCTTCACACAGGAC
3' ss Score
11.18
Exon sequences
Seq C1 exon
GTGTACACTGTGAGATCAATGTTGATGACTGCCATCCCCCCCTTGACCCTGCCTCCCGAAGCCCCAAGTGCTTCAACAATGGCACCTGTGTGGACCAGGTGGGTGGCTATACCTGCACCTGCCCACCAGGCTTCGTCGGGGAGCGGTGTGAGGGTGATGTCAATGAATGTCTCTCCAACCCCTGTGACCCACGTGGCACCCAGAACTGTGTGCAGCGTGTTAATGACTTCCACTGCGAGTGCCGGGCTGGCCACACTG
Seq A exon
GTGCGTGCCTTGGGCAGGTGGGTCGAACGGGTGGGTGGGCAGGGTCAACAGGGATGGCTCCTTACTGTCCCTTCTTCACACAG
Seq C2 exon
GACGCCGCTGTGAGTCAGTCATCAATGGCTGCAGGGGCAAACCTTGCAAGAATGGGGGTGTCTGTGCCGTGGCCTCCAACACCGCCCGTGGATTCATCTGTAGGTGCCCTGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026923-Notch1:NM_008714:23
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(6.5=2.3),PF0000822=EGF=WD(100=44.8),PF0000822=EGF=PU(90.9=34.5)
A:
NA
C2:
PF0000822=EGF=PD(6.1=5.3),PF0000822=EGF=PU(79.4=71.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGTGTGAGGGTGATGTCAAT
R:
CACCCCCATTCTTGCAAGGTT
Band lengths:
175-258
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: