Special

MmuINT0157272 @ mm9

Intron Retention

Gene
ENSMUSG00000029192 | Tbc1d14
Description
TBC1 domain family, member 14 [Source:MGI Symbol;Acc:MGI:1098708]
Coordinates
chr5:36847674-36850355:-
Coord C1 exon
chr5:36850227-36850355
Coord A exon
chr5:36847784-36850226
Coord C2 exon
chr5:36847674-36847783
Length
2443 bp
Sequences
Splice sites
5' ss Seq
CTTGTGAGT
5' ss Score
7.15
3' ss Seq
TGTTTAACATTGTCTCCTAGATG
3' ss Score
8.03
Exon sequences
Seq C1 exon
GTTCAGGGCATGTCCTTTATAGCTGCAGTGTTGATCTTGAACCTCGATACTGCAGATGCCTTTATTGCTTTTTCTAATCTTTTGAATAAACCCTGTCAAATGGCGTTTTTCCGAGTGGACCATGGCCTT
Seq A exon
GTGAGTATGCTCTTTGTATATCCTAGTACCATGTCTTTATGCAGCAAGAACTAGCCAATCATTCTGTCTTTTCAAGGCCTGAAACGCATATTCCCTTTCTAATGGGCTGTTTATAATGAGGGGAGCACTTGAACTTAAGAGTGGAAACCTACGGGCCATCACCTCTCGCATGCACAGATTAATGCATTCTCCTGGAGAGAGTGTCTGAAACACTGTACTCTTTGTGAGGGTGGACGGTGACTTCTGTGCAAGCTAGGGAGATACAACAGCAGCGTTCTCAGCTCTGATGCGTGGAGGGCCGGGGGCTGATTTACACTGCTGCTCACGGTCACAGTGAGATGTGTGCACAGGAGTAAGGTGTGCTCCTGACCATGCTCCCGTACCCCAACGGGGCAGTGCTTTAGTATGCTGTGCAGATAGATGGCCTTTACCATTAGTGGCCTTTAAGAACCTCCCCCACAAACTTCACAGCTGAGTCCTGTGCAGAGTTCAGATGCAGGACAGGCTGAGGAGAGAAGTGGCTTGTCTGAGACATATCTTGTACGTGGGAGAGCTGAGGTTTGAATCCACTTCAGGTCCCAAACCCTGTTCTTTCTGTAAGAAAACTCACTAATCCATCAGCTTTTAAGTTGGCGTTGCTTTGAATTCCTGTTCATTACCACTTGTCGGTCCAGACCCCAAGTCTCTGATGATACATGTCAGCTGGGCACTTCTTCCTCAAATGACCCTTGTTCTCAAGCTGCTGCTCACTCTGGCTGTTAGGGGTGTCCGCTATGGCCCGACTGGAAGATTATTTGGTATTCCATTTCTGTAGCTGAGAGTGGCTTTGGTACAAAGTTCTCACAAGAATTGGTTCTGAGAAAAGTCATAATTGTGAAGAAAGCATTATATAGAGAGATTGTTATTACCTAAGTATTTATAGTTGTAAATATTAGAAGGGTTTAAAATGGGCTAAGGGGAAATGGGTGGTAAGTAAATCTGCCAAGACCCCCAGTGCAGCTGTGTCACACTGCTTTCCCATAAGGAATGGGAAAGACACCTAGGGCTGTAGTCACTCTGTGTCATAGTAGGGAATTAATCTCATAACCACCATCACTTATGGGTAGGACCTTCATGAATTAGCGTTTTTGTCATAGTTTTGTTAAATATTTTGAGGCGAGGTCTTACTGTGTGGCCCAGGCTAGCCTCAAACTCCTGGTCCCCTGCTATCGTCTCTCACGTCTCCCAACTTGTGGGATACGGGGTTTCGGGGTTTCGGTGCTTTAAGTTCTCTTAACTGAGTAGTTACAGCAATTCCTTTCACAAGCAGATGAAAACTTTCTAAGAAAAGGAGTGGCATCTTTAGGAGAGATTCACACCCTGAATAGCTTATTGCTGCTAACTTACTGACTTATTGTCTGCATTAGTCCTGGCTATCAATTTAATTTGTTTGTTTGGTTTTGGAAAAAGGTCTTATCTGATAAGCCAGCTGGCCTTGGATGCAGAAGCCCGCTGTCTCAGGCTCCCAACTGCCAGAGCTATAGGTGTGCGCCATCCCGCCACACTCTTAACTTTCCCATTCTCTGTAGAGTCAGATGATACCTGCTTTGGCCAGTTTGAGCTTTCTCTCTTGAATACAGACTGAAGAGAGGGAGAAGCAGCAGGTGCTGCTGAGTGGGACCTTTGCTCTGGTGACCATCAGGCCAGGTGACTGCTGTGGGCTTTCCTACTCACTGGAGGCCTCTACACACAAGTATCTCTAGACGTTGCCTCCTGTCCCTGTGCTCTACAGTGTAGTCCTGTCAGGAAAATGAGTAAAAGTCAGGGCTGGGCTCTACTTCTGCCCCTGGTGGACGTGTAGAGCAGACCCCCAGCCCAGGCGTGGCTGCTCCCACCTAGCAGGAGCTCTTCTTTTATGTTGGTTGCACCACGCTGTCTCTCCCCTGACCCTGCTTTCTTTCTTTTCTTACAAAGCATGTACGAAGCCTAGCCTCTTTCTGCTTTCTCCTTGTGGGATTTTTCTTCACAGTGGTCAAGGCCTGCATGTTTAAGAAAAACATGCTGTGTTGTCCGTCCCTCATACTCTAGTCTCGTCTCTCCCTCTGGAGGTGCTCACCCTAGGCAGCAGGCAGCCTTGCTTTCCCAGCCGTCCCACACAGCGCTCCAGCAGCTTTCGTGCATTCCAGGGCGTGGTTCAAGTCCCAGCTCTACCCTGACTGGTACTTTGCCCCTGTGTGGCAAGTTAAGCACCTGCTGTGGGTTTCAGTGTCTTCCCCTGTAACTAGAAGAAATGATGGGATACAGTCAGAGCTGCCCTGGGAAGCTGAGAGGCAGAGTTATACTTATCTGCATGTTACCTGGATAACAATTATTTATATTCTAAGTGTGCAAAGCTCTTGACGCTTGTGGATTGAAAAATCATGCTGACGACTAGTTTACTAGTGTGTTTAACATTGTCTCCTAG
Seq C2 exon
ATGTTGACTTACTTTGCTGCATTTGAGGTATTCTTTGAAGAAAACTTGCCGAAATTGTTTGCGCATTTCAAGAAAAACAACTTAACTGCAGATATCTACCTAATCGATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029192-Tbc1d14:NM_133910:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0056613=RabGAP-TBC=FE(18.4=100)

							
A:
NA

							
C2:
PF0056613=RabGAP-TBC=PD(1.2=3.6),PF0056613=RabGAP-TBC=FE(33.8=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000116519





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000031094, ENSMUSP00000098830, ENSMUSP00000114508, ENSMUSP00000115926, ENSMUSP00000117414, ENSMUSP00000119347, ENSMUSP00000121516, ENSMUSP00000121816, ENSMUSP00000131876
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr4:7010782-7014447 
LOW PSI
HsaINT0164001
(TBC1D14)
Human
(hg19)
chr4:7012509-7016174 
LOW PSI
HsaINT0164001
(TBC1D14)
Rat
(rn6)
chr14:79426541-79429106 
ALTERNATIVE
RnoINT0147937
(Tbc1d14)
Cow
(bosTau6)
chr6:118289747-118290889 
LOW PSI
BtaINT0145420
(TBC1D14)
Chicken
(galGal4)
chr4:79491389-79494304 
ALTERNATIVE
GgaINT0069298
(TBC1D14)
Chicken
(galGal3)
chr4:82884678-82887593 
ALTERNATIVE
GgaINT0069298
(TBC1D14)
Zebrafish
(danRer10)
chr7:39427579-39427656 
LOW PSI
DreINT0160562
(tbc1d14)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"