RnoEX0009351 @ rn6
Exon Skipping
Gene
ENSRNOG00000011076 | Ank2
Description
ankyrin 2 [Source:RGD Symbol;Acc:620156]
Coordinates
chr2:231242940-231253949:-
Coord C1 exon
chr2:231253928-231253949
Coord A exon
chr2:231244673-231250903
Coord C2 exon
chr2:231242940-231243014
Length
6231 bp
Sequences
Splice sites
3' ss Seq
GTTTTTCATTCACATCAAAGATG
3' ss Score
3.46
5' ss Seq
AAGGTATTT
5' ss Score
7.64
Exon sequences
Seq C1 exon
ATCTGTATGACATCAGAAAAAA
Seq A exon
ATGATGAGACAGAGTCGACAGAAACATCTGTCCTGAAAAGCCATCTGGTTAATGAAGTTCCTGTCTTAGCAAGTCCGGACTTGCTCTCTGAAGTTTCTGAGATGAAACAAGATTTGATCAAAATGACGGCCATCTTGACCACAGATGTGTCTGATAAGGCAGGTTCCATCAAAGTGAAGGAGCTGGCAAAGGCTGGTGAAGAAGAGCCAGGCGAGCCCTTTGAAATTGTAGAGAGAGTCAAAGAGGACTTAGAGAAGGTGAATGCGATCCTGAGAAGTGGAACGTACATGAGAGACGAAGGCAGTGTGCGGAGTTCTCAGTCTGAGCGGGAGCTAGAGGAGGAATGGGTTATTGTCAGCGATGAGGAAATCGAAGAGGCCAAGCAGCATGCCCCGGTAGAAATCGCTGAACACCCATGTGTAGAGGTCAGAGTAGACAGAGAGACCAAGACCAAAGTAGAGAAGGACTCCACTGGGTTAGTGAACTACCTCACAGATGACCTAAATTCATACACGGGTACTCATGAAAAGAAGCCACAAACAGCTCCAGAAAAGTCAGGGGAGACAAGCCAGGCTTCAGCCATTGTCAAGAGTTCTGAGAGTAATAAAGGCAAGACCTCCCCAGCAGAGGAGAAACAGAGCGCTCAGAAGCAGGTTAAACCGAGCCTAGTGATAAAGAAGCCAGTGCGGCGGAAACTAAAAGAGAAACAGAAACAGAAAGAGGAAAGCCCACAAGGCAGCGAAGAAAAGACTGAACTTAAGAAAGGTAGCTCAGAGGAGTCAGTAGATGAAGACCGGGGCCTGGCCCCTGAACCCCTTCCCACTGCCAAGGCCACCTCTCCTCTGATAGAAGAAACTCCTATTGGTTCCATAAAGGACAAAGTGAAGGCTCTTCAGAAGCGAGTGGAGGATGAGCAGAAAGGTCGAAGCAAGTTGCCAGTCAGAGTCAAAGGCAAAGAGGATGTGCCCAAAAAGACCACTCCCAGGACACACCCAGTTGTGTCGCCCTCTTCAAAGTCCTCTCCTTCCTCTAAAATGGAAAGGCACTCTTCCCTTACTTCCTCTGCAAAAACTGAAAGGCACTCACCAGTGTCACCATCAAGCAAAAATGAGAAACACTCCCCTGTGTCGCCCTCAGCAAAAGCCGAACGACATTCACCAGTATTTTCTGGTAAACCCGAGAAACATTCACCTGGTTCCCCCTCAACCAAAAATGAAAGACATTCCCCTGTGTCATCTATAAAAACAGAACGACACACACCTGTGTCACCTTCAGGCAAAACAGATAAACGTCCACCTGTGCCATCATCTGGAAGAACAGAGAAACATCCTCCAGTGTCACCTGGCAAAACAGAAAAGCGCTCTCCCGGTGCACCTTCTATAAGAACCCCGGAGAAGCAGGCACCTGGGTCTGCCACTGGGAAACATGAAAAGCACCTACCTGTGTCTCCAGGAAAGACAGAAAAACAGCCACCCATATCGCCCACCTCCAAAACTGAACGAATTGAGGAGACAATGTCTGTCCGGGAGCTCATGAAAGCTTTCCAGTCAGGTCAGGACCCATCTAAACACAAAACAGGACTCTTTGAGCACAAATCAGCAAAACAAAAACAGTCACAAGACAAAAGTAAAAGTCGGGTAGAAAAAGAAAAAGGCCACTCTGTAACCCAGAGAGAAACCCAGAGAATAGAAAATCAGACAGCCAAACGTGGCCAGAGATTCCAGGTGACGGGAGCCATGGAATCCAGACGGTTCCGTTCTACCACCATCACCGTTGGGCTCAGGACAGAAGATCCGGTTAGAGAAAGGTTTGAGAGAACCCCCGTTATTAAAACACCCGAGGCAGTTCCACCGGTGGCGGCGGCAGTGGCGGCGGCAGCAGCAGAAGAAAGCCATCGTGGGGCTGAGACCCTTCAAGAGAAGACTGTGGATGAGCAGGAAGACATGGACCTCCAGATCAGCCCAGACAGGAAAACCTCCACTGACTTTTCTGACGTCATCAAGCAAGAGTTAGAAGACAATGACAAATACCAACAATTCCGCCTCACTGAGAACACAGAAAAGGCTCAGATTCATTTAGACCAAGTAATCACGAGTCCCTTCAACACGACATTTCCACTAGATTACATGAAAGATGAGTTCCTCCCAGCTCTGTCTTTACAGAGTGGGGCTTTGGGTGGCAGTTCGGAAAGCCTGAAGCAGGAAGTGATAGCGGGCTCACCTTGTGGCAGCTTGATGGAAGGCACACCTCAGATCAGTTCAGAAGAGAGCTACAAACATGAGGGCCTAGCGGAAACTCCTGAGACAAGTCCAGAGAGTCTTTCTTTCTCACCAAAGAAAAGTAAGGAACAAATTGGAGAGGCCAAGGAAACTATCAAGGTAGAAACGCCCACAGACATTCATTCAGAAAAAGAGCTTCCTATAACCAATGACATTGCTGATAGTTCTGAAAAACAAGGTGCTGGGGTCCCTGGGGATTCAGAGCATGTTCTGAAGGAGGTTACCCAAGTCCCTCCCAAAGATGTGTGCTCCAAACAAGAGGACTGCCCTGGCAGCCACAGTGTATCATTAGCAAATGAGACATGCCAGGCACTTACTGAGGAAGGGTCCTGCAGGGACAGTCAGCTCCCACTTGTTAGTTCAGCTTGTAAGACACAAGCAGTAAGTGAAACTCAGGAATCCTTAGCTACCTCAGAGGTGACAAAGGCCTTCCCACCATCTGATGCTACTGTCAAGACAGTTGAGGGAACAGAACCAAAACCCCAGGGAGTCATTAGAAGTCCCCAAGGGCTAGAACTCCCTCTCCATAACCGGGATAGTGAGGTCCTCAGCCCAATGGCTGATGAATCATTAGCAGTCAGCCACAAAGACTCTCTGGAAGCCAGCCCTGTGCTAGAAGATAACTCCTCACACAAAACTCCCGATTCTCTGGAACCAAGTCCCCTGAAAGAGTCCCCTTGCAGGGACTCCCTGGAAAGCAGCCCAGTTGAGCCTAAAATGAAGGCAGGAATTCTCCCAAGTCACTTTCCTCTCCCTGCAGCTATTGCCAAAACAGATCTTGTTGCTGAAGTGGCTTCCATGCGTTCTCGGCTGCTTCGAGATCCCGATGGCAGTGCTGAGGATGACAGTCTAGAGCAGACATCACTCATGGAGAGCTCAGGGAAAAGCCCCCTCTCCCCTGACACCCCCAGCTCTGAAGAAGTTAGTTATGAGGTCACACCCAAACCTTCAGATTCAAGTACACCCAAACCTGCTGTGATTCATGAATGTGCAGAGGAGGATGACTCTGAAAACGGGGAGAAAAAAAGGTTCACACCAGAAGAGGAAATGTTCAAAATGGTAACGAAAATTAAAACGTTTGATGAACTTGAGCAAGAAGCAAAGCAAAAAAGGGACTACAAAAGAGAGCCCAGGCAAGATGAATCCTCCTCATCCTCGGACCCCGATGCTGACTGTTCAGCAGAAGTGGACGAACAGAAACAGATGGGGAGCACAGAGGGTGAGAGTGACGTCCCTGTCTTGGTGACTTCAGAGAGCAGAAAGGCTTCTTCCTCCTCAGAGAGTGAACCTGAGCTGACACAGCTGAGTAAAGGTGCGGACTCAGGTCTTCTGACAGAGCCAGTTATTCGAGTGCAACCTCCATCTCCCCTCCCATCCAGCATAGACTCTAATTCCAGCCCGGAAGAAGCACAGTTCCAGCCCATAGTTCCCAAGCAATATACTTTCAAGATGAACGAGGAGGTTAAAGAAGACCCGGGTAACCCAGAAGAAGACAAAGATTGCAAATCACACTTAGCTGAAGACAGTCAGACTCATTCTGCTGATGGTGCCGATGGGTCTCATGCTGACCTGAACAGAGAGACTCCTCAGTTAGAAGCCTGTGATGGCCATGGTTGTAAGGCTGTGAGTCCTAGCAACTCAGCCACTCCTGTCTCCCTAGGAGTTCAGAGTCCAGAGTGTCATGATGTTGATAAGCCCCTGGCCATTGATAACGATTCACTAGCTCTCCAGGATACTCATGGAAGTGACCTTGAAGAAAGAGAGTTTGATCCTTCCAGAGTGGAGTCTACACAAGCAAGTCTTCCCAGTGAACACTCGTCCTTGTCTTCTTCGTCTCATTGTGCGGTACCTGAAGAAAATGAATCAGCTAAAGAAATATCTTCTCCATCTTCCCCTGTAAAAGTAGAGGTCACAGTAACTGACCCAGTTTTGGAGAGCATGTCAGAGGACTGTCCTACTCAAGAGGCATCTACTACAACTCACACAGAAAGGTTTGCCATGGACGGTCCAGTGTCTGATATAGCCGAGACTGATGAAAATTCTCATCCTCAAATCACCAGCCCTTATGAAAATGTTGCTTCCTCATCCTTTTTCTCTGGTGAACCCAGCAATTTCCAAACAGATACCTGTCATCCTACAGTTGTTCATTCACCTGAAGTGTATTCTGTTATTATCAGATCCTCTCCTGAGGATGTCATAATGACCAGCTCCTCTAGTAGAACGGACTCAGGTGAAGCATCTAATTGTGAGGGCCATGACCTAGACACTGAATGTGAGCAAAAAAGTGCTCTGTGGCCAATGCAGTCTGATGAGCCCCCCTTGTCTGTAGCACCCACGACACCAAACGCACCAGTAGTGACTGGTGAACAAGTAAGCAAAGTCATCATCACCAAAACGGATGTGGATGCTGACTCTTGGAGCGAGATACGTGAAGATGACGCAGCCTTTGAAGCTCGAGTGAAAGAGGAAGAGCAGAAGATATTTGGTTTGATGGTAGACAGACAGTCACAGGGCACCACCCCTGATACCACCCCTGCTAGAACTCCAACTGAAGAGGGGACCCCGACAAGTGAACAAAATCCATTCCTCTTTCAGGAAGGAAAGCTGTTTGAGATGACCCGAAGTGGTGCTATTGATATGACCAAAAGGTCCTATGCGGATGAAAGTTTGCACTTCTTCCAAATCGGCCAAGACTCCAATGAAGAGACTATCTCTGAAGACTTGAAGGAAGGGGCCACTGGGGCTGAGCCTCCACAGACGGAGACTACTAGTGAGTCACTGGAACTCTCAGGACCCAAAGAAGCAATGGATGACGAAGGAGAATTAGTTCCTGATGATGTAAGTGAGGAAATAGAGGATTTACCCGCCTCGGATGCTGACCTTGACTCCAAAGTGGTAATTTCAGCTTCCACAGAAACACCCACCAAAGAGGCTGTATCCACAGTGGCCGAGGAGCCCGCCACCATGCAGTGGAGTGATTCTCTAAGCACTGTGAAGCAGACATCTTGCCCTACTTTCCCCGAACCTGTTGGTCAGCTGGACTTCTCCACTGTCACTAGGTCTGTTTATTCGGATCGGGATGATGAGTCCCCAGATTCTTCTCCCGAGGAACAGAAGTCTGTGATTGAGATCCCTACTGCACCCATGGAAAACGTGCCTTCTGCTGAAATCAAACCCCAGATTCCTATCAGGACTCTCCCCACTTCAGTGTCAGCCCCTCCATCTGCAGAGGATGAGAGTGCATTTTCTGATGATTTCCCATCTGGTCTGGATGGGGAGAGTGAGGAGGATGGGGCAAAACCAAAGTCCAAAATCCCCATCAAAGCACCCCCCCAAAGAACTGAGTGGCACCCCTCCCATCCAGACATATCTCTCCAGAAGTCAGGTGTCCCCCAGGGACAAGACGTGTTAAGCCGAGGACCAGATGGTAGAAGCAAGTCAGAATCAGACGCTAGCTCCTTGGATGCTAAGACCAAATGCCCAGTGAAAGCCAGAAGTTACATTGAGACAGAAACAGAGAGCAGGGAGAGGGCAGAGGGGTTTGAGTCAGAATCAGAAGAAGGGGCCACAAAACCAAAGCTCTTTGCATCCCGACTGCCGGTGAAGAGCAGAAGCACCTCATCTTCCAGCAGGACAGGCACGAGCCCCACAAGAGAGAGTAGGGAGCACTTCTTTGACCTTTACCGGAACTCCATAGAATTCTTTGAGGAGATTAGTGATGAGGCTTCCAAATTAGTAGACAGGCTTACACAGTCAGAAAGGGAGCAAGAGCCACCCTCAGACGACGAAAGTAGCAGTGCCCTGGAAGTGTCAGTCATTGAGAATCTGCCACCTGTTGACACTGAGCACTCAGCTCCTGAGGACATCTTTGACACAAGGCCCATTTGGGATGAGTCCATTGAGACTATGATTGAACGCATCCCTGATGAAAATGGCCATGACCGAGCTGAAG
Seq C2 exon
ATCCCCAGGATGAGCAGGAGCGGATGGAAGAGAGGCTGGCTTACATTGCAGATCACCTTGGCTTCAGCTGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000011076_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.989 A=0.923 C2=0.397
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0053117=Death=PU(19.0=61.5)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 31285321
Giant ankB (contains HsaEX0004136) localizes to periodic axonal plasma membrane domains through L1 cell-adhesion molecule protein, where it couples microtubules to the plasma membrane and prevents microtubule entry into nascent axon branches. Giant ankB mutation or deficiency results in a dominantly inherited impairment in selected communicative and social behaviors combined with superior executive function.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]