RnoEX0045254 @ rn6
Exon Skipping
Gene
ENSRNOG00000012208 | Itgb7
Description
integrin subunit beta 7 [Source:RGD Symbol;Acc:2929]
Coordinates
chr7:143820900-143821955:-
Coord C1 exon
chr7:143821750-143821955
Coord A exon
chr7:143821330-143821488
Coord C2 exon
chr7:143820900-143821205
Length
159 bp
Sequences
Splice sites
3' ss Seq
ATGCCTTGTCTCCATCAGAGGGA
3' ss Score
-5.83
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GGACTGCGCGGAGTGTGGGGCGTTTGGTACGGGTCCCCTGGCAGCCAACTGCAGCGCGGCTTGTGCTGACGTGAATGTGACCTTGGCCTTGGCCCCCAATTTGGATGATGGTTGGTGCAAAGAGAGGACGCTAGACAACCAGCTGTTCTTCTTCCTGGTGGAGAATTCGGCCAGAGGGGTCATACTGAGAGTGAGACCCCAAGAGA
Seq A exon
GGAGCAGACCACACCCGTGCCATCATACTGGGCTGCGTAGGGGGCATTGTGGCAGTGGGATTAGGGCTGGTCCTGGCTTACCGGCTCTCAGTGGAAGTCTATGACCGCCTTGAGTACAGCCGCTTTGAGAAGGAGAGGCAGCAACTCAACTGGAAGCAG
Seq C2 exon
GACAGCAATCCTCTCTACAAAAGTGCGGTCACAACTACCGTCAACCCTCGCTTCCAAGGGGGCAACAAACAGTCGCTGTCCCTCCCTCTGACCCAGGAGGCTGACTGACTTAGGATTCTTGTCTTGGAGGACAGAGGGGGCAGTAGGGCAGGGGCAGTGTCTGTTGCAAAGTTTTTTTTCAGACTGGCCTTCAGAGGGCAGCGTAACCACGGCAACAGCCACCCCACGTGAAGGGCTGGTCCTTCCACCATAAAGTTCTGCCTCAGACTTTCGGCCTGTGGCCTGTACTTCACCCCGGGACAAAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000012208-'17-16,'17-15,18-16
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.029
Domain overlap (PFAM):
C1:
NO
A:
PF087256=Integrin_b_cyt=PU(53.2=46.3)
C2:
PF087256=Integrin_b_cyt=PD(42.6=55.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Mouse
(mm10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCCCAATTTGGATGATGGT
R:
CCCCTCTGTCCTCCAAGACAA
Band lengths:
254-413
Functional annotations
There are 1 annotated functions for this event
PMID: 12606711
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, surface plasmon resonance. ELM ID: ELMI001554; ELM sequence: QDSNPLYK; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]