RnoEX0054907 @ rn6
Exon Skipping
Gene
ENSRNOG00000004740 | Mmadhc
Description
methylmalonic aciduria and homocystinuria, cblD type [Source:RGD Symbol;Acc:1303272]
Coordinates
chr3:35797564-35801614:-
Coord C1 exon
chr3:35801350-35801614
Coord A exon
chr3:35800982-35801038
Coord C2 exon
chr3:35797564-35797708
Length
57 bp
Sequences
Splice sites
3' ss Seq
TTGTTTTTGCTCTCTCCCAGGGA
3' ss Score
10.85
5' ss Seq
CATGTAAGT
5' ss Score
8.31
Exon sequences
Seq C1 exon
CAAAGACTCAGCTAAGACTGGTGCTGAGTCCTGTAAATATTCCCAATTTGGTCCCACCCCGCCGTGATCCACCCATCAGTTTACCCAATGAAAGACTAGCTCACCTTCTGAAGCCCTGTGATCAGCCTCTACTCGAAGATCGACCGACAGCATCGATGCGCTCGGAGGCAACTACTCAGGTCTGGGCGTCAACAGCGCCTGCCTGGACCGCCATTTTGACAGTGGACGTGTTGAGGGACTGGATCAGCTGGCCGTGTGGTGACTG
Seq A exon
GGATACTTTGCAGAGGGGAAAAGTCTGCGTCCGCCTTCTTCACTAGAAATGGCCCAT
Seq C2 exon
GTGCTCTGTAACAGAGCCAGACTGGTTTCCTATCTCCCAGGATTTTGTTCTCTAGTGAAAAGAGTTATCAATCCAAGAGCCTTTTCAACTGCAGGATCGTCAGGTTCCGATGAGTCTCACGTGGCCACTGCACCTCCAGATATAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000004740-'0-3,'0-0,5-3
Average complexity
C1
Mappability confidence:
91%=100=83%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.000 C2=0.337
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
PF102294=DUF2246=PU(11.6=65.3)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTGTTGAGGGACTGGATCA
R:
AACCTGACGATCCTGCAGTTG
Band lengths:
146-203
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]