RnoEX0078607 @ rn6
Exon Skipping
Gene
ENSRNOG00000005309 | Scn8a
Description
sodium voltage-gated channel alpha subunit 8 [Source:RGD Symbol;Acc:3638]
Coordinates
chr7:142650181-142653394:+
Coord C1 exon
chr7:142650181-142650422
Coord A exon
chr7:142650594-142650724
Coord C2 exon
chr7:142653221-142653394
Length
131 bp
Sequences
Splice sites
3' ss Seq
GCCACCCGCGCTTCTGCCAGGCA
3' ss Score
6.1
5' ss Seq
TGGGTTGGT
5' ss Score
0.35
Exon sequences
Seq C1 exon
CAGAGCTGGAAGAGTCTCAGAGAAAGTGCCCACCGTGCTGGTATAAGTTTGCCAACACTTTCCTCATCTGGGAGTGTCACCCCTACTGGATAAAACTGAAGGAGATCGTGAACTTAATCGTCATGGACCCTTTTGTAGACTTAGCCATCACCATCTGCATCGTTCTGAATACGCTATTTATGGCAATGGAGCACCATCCCATGACACCACAGTTCGAACACGTCTTGGCCGTAGGAAATCTG
Seq A exon
GCACCTTCAGCTGCGCCTTCCCTGGAGAACTCTGAAGATGCCTCTTAGAGCTGTTGGCAGGAAGCCAGCTACAGTGGCCGAGTGGGAGACAGGACAGCGAGTTGGTCCAGCGCCTGCGGCAGATCTAATGG
Seq C2 exon
GTGTTCACCGGGATCTTCACGGCGGAAATGTTTCTGAAGCTCATAGCCATGGACCCCTACTATTATTTCCAAGAAGGCTGGAACATTTTTGACGGATTTATTGTCTCCCTCAGTTTAATGGAGCTGAGTCTCGCAGATGTGGAGGGGCTCTCAGTGCTGCGGTCTTTCCGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000005309_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=0.533 C2=0.000
Domain overlap (PFAM):
C1:
PF119333=DUF3451=PD(6.9=21.0),PF0052026=Ion_trans=PU(1.6=3.7)
A:
NO
C2:
PF0052026=Ion_trans=FE(30.0=100)
Main Inclusion Isoform:
ENSRNOT00000008160fB12995
Other Inclusion Isoforms:
NA
Associated events
Conservation
Human
(hg19)
No conservation detected
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTCAGAGAAAGTGCCCACC
R:
CGTGAAGATCCCGGTGAACAC
Band lengths:
250-381
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]