RnoEX6017285 @ rn6
Exon Skipping
Gene
ENSRNOG00000056184 | Lrp2
Description
LDL receptor related protein 2 [Source:RGD Symbol;Acc:68407]
Coordinates
chr3:55706960-55711254:-
Coord C1 exon
chr3:55711053-55711254
Coord A exon
chr3:55707837-55708132
Coord C2 exon
chr3:55706960-55707476
Length
296 bp
Sequences
Splice sites
3' ss Seq
TCCTTTGTCTTGTAACGCAGGTG
3' ss Score
8.54
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
Exon sequences
Seq C1 exon
AGCTTCAGAACTGTTCCAGCACTCAGTTTACCTGTGTCAACAGCAGACCTCCCAACAGGAGGTGCATCCCACAGTACTGGGTCTGTGACGGTGATGCGGACTGCTCGGACGCCCTGGACGAGCTGCAGAATTGCACCATGAGAACCTGCTCTGCAGGGGAGTTCAGCTGTGCAAACGGACGATGTGTCAGGCAGTCATTCAG
Seq A exon
GTGTGATCGGCGCAATGACTGTGGAGACTACAGTGATGAGAGGGGCTGCTCGTACCCACCCTGCCATGCAAATCAATTTACGTGTCAGAACGGGCGGTGTATCCCTAGGTTCTTTGTTTGTGATGAGGACAATGACTGTGGAGATGGTTCTGATGAGCAGGAGCACCTGTGTCACACCCCAGAACCCACATGCCCCCTTCATCAATTCCGGTGTGACAACGGGCACTGCATCGAGATGGGGCGAGTCTGTAACCATGTGGACGACTGCTCAGACAACAGCGATGAGAAAGGCTGTG
Seq C2 exon
GCATTAACGAGTGCCTAGATTCTTCAATCAGTCGCTGTGACCACAACTGTACAGATACCATAACTAGTTTCTACTGTTCCTGTCTCCCTGGCTACAAGCTCATGTCTGACAAACGCTCTTGCGTGGATATTGACGAATGCAAGGAGTCACCCCAGCTCTGTAGCCAGAAGTGTGAGAATGTGGTAGGCTCCTATATTTGCAAGTGTGCCCCTGGCTACATCCGTGAGCCAGATGGGAAGAGCTGCCGGCAGAATAGTAACATCGAGCCCTATCTCATCTTTAGCAACCGTTACTATATAAGAAACTTAACTACAGATGGCTCATCTTACTCCCTGATTTTGCAAGGATTGGGCAATGTTGTGGCCCTGGACTTTGATAGAGTAGAAAAGAGGCTGTATTGGATTGATGCAGAGAAGCAAATCATTGAGAGGATGTTTTTGAATAAGACAAACCGGGAGACCATCATAAACCACAGGTTAAGACGTGCTGAAAGTCTGGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000056184-'61-70,'61-69,62-70=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=63.2),PF0005713=Ldl_recept_a=PU(54.1=29.4)
A:
PF0005713=Ldl_recept_a=PD(43.2=16.0),PF0005713=Ldl_recept_a=WD(100=39.0),PF0005713=Ldl_recept_a=WD(100=37.0)
C2:
PF126622=cEGF=WD(100=13.9),PF146701=FXa_inhibition=WD(100=20.8),PF0005812=Ldl_recept_b=WD(100=23.7),PF0005812=Ldl_recept_b=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTTCAGCTGTGCAAACGGA
R:
TACTATTCTGCCGGCAGCTCT
Band lengths:
302-598
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]