Special

FBgn0000346 @ dm6

Biotype
protein_coding
Gene Symbol
comt
Description
The gene comatose is referred to in FlyBase by the symbol Dmelcomt (CG1618, FBgn0000346). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:13259021..13262488. Its molecular function is described by: ATP binding; ATPase activity. It is involved in the biological process described with 14 unique terms, many of which group under: protein-containing complex subunit organization; regulation of neuromuscular synaptic transmission; Golgi organization; organelle localization by membrane tethering; homeostatic process. 53 alleles are reported. The phenotypes of these alleles manifest in: vesicle; cytoplasm; intracellular membrane-bounded organelle; multi-tissue structure; multi-cell-component structure. The phenotypic classes of alleles include: paralytic; behavior defective; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chrX:13259021-13262488:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Intron Retention
68
chrX:13261664-13261731
+
3.54
55.46
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000073969 NSF 2-to-1
Human hg19 ENSG00000073969 NSF 2-to-1
Mouse mm10 ENSMUSG00000034187 Nsf 2-to-1
Mouse mm9 ENSMUSG00000034187 Nsf 2-to-1
Cow bosTau6 ENSBTAG00000008442 NSF 2-to-1
Chicken galGal4 ENSGALG00000001055 NSF 2-to-2
Chicken galGal3 ENSGALG00000001055 E1C646_CHICK 2-to-2
Zebrafish danRer10 ENSDARG00000007654 nsfa 2-to-2
Zebrafish danRer10 ENSDARG00000038991 nsfb 2-to-2