Special

FBgn0001308 @ dm6

Biotype
protein_coding
Gene Symbol
Khc
Description
The gene Kinesin heavy chain is referred to in FlyBase by the symbol DmelKhc (CG7765, FBgn0001308). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:16266960..16271971. Its molecular function is described by 7 unique terms, many of which group under: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; hydrolase activity; pyrophosphatase activity; catalytic activity; nucleoside-triphosphatase activity. It is involved in the biological process described with 30 unique terms, many of which group under: microtubule sliding; protein-containing complex disassembly; cell cycle; visual system development; regulation of macromolecule metabolic process. 126 alleles are reported. The phenotypes of these alleles manifest in: intracellular; female reproductive system; cell projection; actin filament; female-specific anatomical entity. The phenotypic classes of alleles include: phenotype; increased mortality during development; behavior defective; visible. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period, in adult female stages.
Coordinates
chr2R:16266960-16271971:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Intron Retention
138
chr2R:16269656-16269793
-
3.43
93.75
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000155980 KIF5A 1-to-3
Human hg38 ENSG00000168280 KIF5C 1-to-3
Human hg38 ENSG00000170759 KIF5B 1-to-3
Human hg19 ENSG00000155980 KIF5A 1-to-3
Human hg19 ENSG00000168280 KIF5C 1-to-3
Human hg19 ENSG00000170759 KIF5B 1-to-3
Mouse mm10 ENSMUSG00000006740 Kif5b 1-to-3
Mouse mm10 ENSMUSG00000026764 Kif5c 1-to-3
Mouse mm10 ENSMUSG00000074657 Kif5a 1-to-3
Mouse mm9 ENSMUSG00000006740 Kif5b 1-to-3
Mouse mm9 ENSMUSG00000026764 Kif5c 1-to-3
Mouse mm9 ENSMUSG00000074657 Kif5a 1-to-3
Rat rn6 ENSRNOG00000004680 Kif5c 1-to-3
Rat rn6 ENSRNOG00000005299 Kif5a 1-to-3
Rat rn6 ENSRNOG00000017466 Kif5b 1-to-3
Cow bosTau6 ENSBTAG00000002280 KIF5B 1-to-3
Cow bosTau6 ENSBTAG00000018125 KIF5C 1-to-3
Cow bosTau6 ENSBTAG00000021336 KIF5A 1-to-3
Chicken galGal4 ENSGALG00000007215 KIF5B 1-to-3
Chicken galGal4 ENSGALG00000012462 kif5c 1-to-3
Chicken galGal3 ENSGALG00000007215 E1C3A1_CHICK 1-to-3
Chicken galGal3 ENSGALG00000012462 Q6V1L3_CHICK 1-to-3
Zebrafish danRer10 ENSDARG00000059818 kif5ab 1-to-5
Zebrafish danRer10 ENSDARG00000074131 kif5ba 1-to-5
Zebrafish danRer10 ENSDARG00000076027 kif5c 1-to-5
Zebrafish danRer10 ENSDARG00000098936 kif5aa 1-to-5
Zebrafish danRer10 ENSDARG00000103394 kif5bb 1-to-5