FBgn0004516 @ dm6
Biotype
protein_coding
Gene Symbol
Gad1
Description
The gene Glutamic acid decarboxylase 1 is referred to in FlyBase by the symbol DmelGad1 (CG14994, FBgn0004516). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3L:4074077..4088744. Its molecular function is described by: glutamate decarboxylase activity; pyridoxal phosphate binding. It is involved in the biological process described with 8 unique terms, many of which group under: multicellular organismal process; cell junction organization; behavior; cellular component organization; response to abiotic stimulus. 39 alleles are reported. The phenotypes of these alleles manifest in: bouton; adult mushroom body anterior paired lateral cell; neuromuscular junction. The phenotypic classes of alleles include: phenotype; increased mortality during development; sensory perception defective; behavior defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.
Coordinates
chr3L:4074077-4088744:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000128683 | GAD1 | 1-to-2 |
| Human | hg38 | ENSG00000136750 | GAD2 | 1-to-2 |
| Human | hg19 | ENSG00000128683 | GAD1 | 1-to-2 |
| Human | hg19 | ENSG00000136750 | GAD2 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000026787 | Gad2 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000070880 | Gad1 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000026787 | Gad2 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000070880 | Gad1 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000090665 | AC101882.1 | 1-to-3 |
| Rat | rn6 | ENSRNOG00000000007 | Gad1 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000018200 | Gad2 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000000531 | 1-to-3 | |
| Cow | bosTau6 | ENSBTAG00000007258 | GAD1 | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000008056 | GAD2 | 1-to-3 |
| Zebrafish | danRer10 | ENSDARG00000015537 | gad2 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000027419 | gad1b | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000055370 | zgc:163121 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000093411 | gad1a | 1-to-4 |