FBgn0004606 @ dm6
Biotype
protein_coding
Gene Symbol
zfh1
Description
The gene Zn finger homeodomain 1 is referred to in FlyBase by the symbol Dmelzfh1 (CG1322, FBgn0004606). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:30765926..30789202. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with 12 unique terms, many of which group under: organic cyclic compound biosynthetic process; mesoderm development; cell motility; negative regulation of muscle cell differentiation; nephrocyte differentiation. 45 alleles are reported. The phenotypes of these alleles manifest in: germline cell; somatic stem cell; trachea; A1-7 dorsal acute muscle 1; intracellular. The phenotypic classes of alleles include: female sterile; phenotype; increased mortality during development; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis.
Coordinates
chr3R:30765926-30789202:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000148516 | ZEB1 | 1-to-2 |
Human | hg38 | ENSG00000169554 | ZEB2 | 1-to-2 |
Human | hg19 | ENSG00000148516 | ZEB1 | 1-to-2 |
Human | hg19 | ENSG00000169554 | ZEB2 | 1-to-2 |
Mouse | mm10 | ENSMUSG00000024238 | Zeb1 | 1-to-2 |
Mouse | mm10 | ENSMUSG00000026872 | Zeb2 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000024238 | Zeb1 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000026872 | Zeb2 | 1-to-2 |
Rat | rn6 | ENSRNOG00000004677 | Zeb2 | 1-to-2 |
Rat | rn6 | ENSRNOG00000017863 | Zeb1 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000012615 | ZEB2 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000020053 | ZEB1 | 1-to-2 |
Chicken | galGal4 | ENSGALG00000007260 | ZEB1 | 1-to-2 |
Chicken | galGal3 | ENSGALG00000007260 | F1NB51_CHICK | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000013207 | zeb1b | 1-to-4 |
Zebrafish | danRer10 | ENSDARG00000016788 | zeb1a | 1-to-4 |
Zebrafish | danRer10 | ENSDARG00000062338 | zeb2a | 1-to-4 |
Zebrafish | danRer10 | ENSDARG00000078416 | zeb2b | 1-to-4 |