Special

FBgn0004606 @ dm6

Biotype
protein_coding
Gene Symbol
zfh1
Description
The gene Zn finger homeodomain 1 is referred to in FlyBase by the symbol Dmelzfh1 (CG1322, FBgn0004606). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:30765926..30789202. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with 12 unique terms, many of which group under: organic cyclic compound biosynthetic process; mesoderm development; cell motility; negative regulation of muscle cell differentiation; nephrocyte differentiation. 45 alleles are reported. The phenotypes of these alleles manifest in: germline cell; somatic stem cell; trachea; A1-7 dorsal acute muscle 1; intracellular. The phenotypic classes of alleles include: female sterile; phenotype; increased mortality during development; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis.
Coordinates
chr3R:30765926-30789202:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
1999
chr3R:30783943-30785941
+
99.99
0.53
1
Intron Retention
292
chr3R:30783651-30783942
+
27.18
96.49
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000148516 ZEB1 1-to-2
Human hg38 ENSG00000169554 ZEB2 1-to-2
Human hg19 ENSG00000148516 ZEB1 1-to-2
Human hg19 ENSG00000169554 ZEB2 1-to-2
Mouse mm10 ENSMUSG00000024238 Zeb1 1-to-2
Mouse mm10 ENSMUSG00000026872 Zeb2 1-to-2
Mouse mm9 ENSMUSG00000024238 Zeb1 1-to-2
Mouse mm9 ENSMUSG00000026872 Zeb2 1-to-2
Rat rn6 ENSRNOG00000004677 Zeb2 1-to-2
Rat rn6 ENSRNOG00000017863 Zeb1 1-to-2
Cow bosTau6 ENSBTAG00000012615 ZEB2 1-to-2
Cow bosTau6 ENSBTAG00000020053 ZEB1 1-to-2
Chicken galGal4 ENSGALG00000007260 ZEB1 1-to-2
Chicken galGal3 ENSGALG00000007260 F1NB51_CHICK 1-to-2
Zebrafish danRer10 ENSDARG00000013207 zeb1b 1-to-4
Zebrafish danRer10 ENSDARG00000016788 zeb1a 1-to-4
Zebrafish danRer10 ENSDARG00000062338 zeb2a 1-to-4
Zebrafish danRer10 ENSDARG00000078416 zeb2b 1-to-4