Special

FBgn0011589 @ dm6

Biotype
protein_coding
Gene Symbol
Elk
Description
The gene Eag-like K[+] channel is referred to in FlyBase by the symbol DmelElk (CG5076, FBgn0011589). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:17873939..17926695. Its molecular function is described by: voltage-gated potassium channel activity; voltage-gated cation channel activity. It is involved in the biological process described with: regulation of membrane potential; potassium ion transmembrane transport; potassium ion transport. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.
Coordinates
chr2R:17873939-17926695:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
+
49.96
43.57
0
Alternative 3'ss
12
chr2R:17914089-17914100
+
50.04
43.57
0
Alternative 3'ss
0
NA
+
61.17
55.89
0
Alternative 3'ss
15
chr2R:17907647-17907661
+
38.83
55.89
0
Intron Retention
954
chr2R:17873980-17874933
+
67.2
95.07
0
Intron Retention
1221
chr2R:17912880-17914100
+
27.14
53.41
0
Intron Retention
506
chr2R:17914281-17914786
+
20.32
47.98
0
Intron Retention
508
chr2R:17914906-17915413
+
11.01
28.78
0
Intron Retention
3253
chr2R:17915495-17918747
+
5.97
25.42
0
Intron Retention
603
chr2R:17921296-17921898
+
7.5
32.85
0
Intron Retention
141
chr2R:17901819-17901959
+
8.49
40.22
0
Intron Retention
3967
chr2R:17903680-17907646
+
21.43
39.14
0
Intron Retention
459
chr2R:17907907-17908365
+
10.62
72.22
0
Intron Retention
485
chr2R:17908595-17909079
+
7.11
43.22
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000089558 KCNH4 1-to-3
Human hg38 ENSG00000135519 KCNH3 1-to-3
Human hg38 ENSG00000183960 KCNH8 1-to-3
Human hg19 ENSG00000089558 KCNH4 1-to-3
Human hg19 ENSG00000135519 KCNH3 1-to-3
Human hg19 ENSG00000183960 KCNH8 1-to-3
Mouse mm10 ENSMUSG00000035355 Kcnh4 1-to-3
Mouse mm10 ENSMUSG00000035580 Kcnh8 1-to-3
Mouse mm10 ENSMUSG00000037579 Kcnh3 1-to-3
Mouse mm9 ENSMUSG00000035355 Kcnh4 1-to-3
Mouse mm9 ENSMUSG00000035580 Kcnh8 1-to-3
Mouse mm9 ENSMUSG00000037579 Kcnh3 1-to-3
Rat rn6 ENSRNOG00000018790 Kcnh4 1-to-3
Rat rn6 ENSRNOG00000057315 Kcnh3 1-to-3
Rat rn6 ENSRNOG00000058626 Kcnh8 1-to-3
Cow bosTau6 ENSBTAG00000001195 KCNH4 1-to-3
Cow bosTau6 ENSBTAG00000012798 KCNH8 1-to-3
Cow bosTau6 ENSBTAG00000019277 KCNH3 1-to-3
Chicken galGal4 ENSGALG00000003354 KCNH4 1-to-2
Chicken galGal4 ENSGALG00000011262 KCNH8 1-to-2
Chicken galGal3 ENSGALG00000003354 KCNH4 1-to-2
Chicken galGal3 ENSGALG00000011262 KCNH8 1-to-2
Zebrafish danRer10 ENSDARG00000061990 kcnh4b 1-to-4
Zebrafish danRer10 ENSDARG00000062565 kcnh4a 1-to-4
Zebrafish danRer10 ENSDARG00000062640 kcnh8 1-to-4
Zebrafish danRer10 ENSDARG00000069560 kcnh3 1-to-4