Special

FBgn0025802 @ dm6

Biotype
protein_coding
Gene Symbol
Sbf
Description
The gene SET domain binding factor is referred to in FlyBase by the symbol DmelSbf (CG6939, FBgn0025802). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:11789293..11796948. Its molecular function is described by 6 unique terms, many of which group under: binding; protein binding; enzyme binding; phosphatidylinositol 3-kinase catalytic subunit binding; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with 8 unique terms, many of which group under: vesicle-mediated transport; mitotic cell cycle; internal peptidyl-lysine acetylation; establishment of localization in cell; heterocycle biosynthetic process. 15 alleles are reported. The phenotypes of these alleles manifest in: fat body; autolysosome; macrophage. The phenotypic classes of alleles include: some die during pharate adult stage; viable; female semi-sterile; starvation stress response defective; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr3R:11789293-11796948:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Intron Retention
349
chr3R:11796495-11796843
-
21.41
100
0
Intron Retention
59
chr3R:11790164-11790222
-
3.57
77.16
0
Intron Retention
59
chr3R:11790022-11790080
-
4.52
74.87
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000100241 SBF1 1-to-2
Human hg38 ENSG00000133812 SBF2 1-to-2
Human hg19 ENSG00000100241 SBF1 1-to-2
Human hg19 ENSG00000133812 SBF2 1-to-2
Mouse mm10 ENSMUSG00000036529 Sbf1 1-to-2
Mouse mm10 ENSMUSG00000038371 Sbf2 1-to-2
Mouse mm9 ENSMUSG00000036529 Sbf1 1-to-2
Mouse mm9 ENSMUSG00000038371 Sbf2 1-to-2
Rat rn6 ENSRNOG00000008392 Sbf1 1-to-2
Rat rn6 ENSRNOG00000009812 Sbf2 1-to-2
Cow bosTau6 ENSBTAG00000021337 SBF1 1-to-2
Cow bosTau6 ENSBTAG00000043981 SBF2 1-to-2
Chicken galGal4 ENSGALG00000005716 SBF2 1-to-4
Chicken galGal3 ENSGALG00000005716 SBF2 1-to-4
Zebrafish danRer10 ENSDARG00000059460 sbf2 1-to-2
Zebrafish danRer10 ENSDARG00000062968 sbf1 1-to-2