Special

FBgn0026376 @ dm6

Biotype
protein_coding
Gene Symbol
Rgl
Description
The gene Ral guanine nucleotide dissociation stimulator-like is referred to in FlyBase by the symbol DmelRgl (CG8865, FBgn0026376). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 3L:13906897..13925335. Its molecular function is described by: Ral guanyl-nucleotide exchange factor activity; Ras GTPase binding. It is involved in the biological process described with: regulation of Ras protein signal transduction; small GTPase mediated signal transduction; activation of GTPase activity. 31 alleles are reported. The phenotypes of these alleles manifest in: external compound sense organ; anatomical group; nervous system; somatic cell; mechanosensory system. The phenotypic classes of alleles include: visible; lethal; viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed during late pupal stages.
Coordinates
chr3L:13906897-13925335:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
564
chr3L:13913962-13914525
-
48.36
97.36
0
Intron Retention
4665
chr3L:13914526-13919190
-
10.25
58.14
0
Intron Retention
72
chr3L:13909184-13909255
-
3.33
62.79
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000143344 RGL1 1-to-5
Human hg38 ENSG00000159496 RGL4 1-to-5
Human hg38 ENSG00000160271 RALGDS 1-to-5
Human hg38 ENSG00000205517 RGL3 1-to-5
Human hg38 ENSG00000237441 RGL2 1-to-5
Human hg19 ENSG00000143344 RGL1 1-to-5
Human hg19 ENSG00000159496 RGL4 1-to-5
Human hg19 ENSG00000160271 RALGDS 1-to-5
Human hg19 ENSG00000205517 RGL3 1-to-5
Human hg19 ENSG00000237441 RGL2 1-to-5
Mouse mm10 ENSMUSG00000026482 Rgl1 1-to-4
Mouse mm10 ENSMUSG00000026821 Ralgds 1-to-4
Mouse mm10 ENSMUSG00000040146 Rgl3 1-to-4
Mouse mm10 ENSMUSG00000041354 Rgl2 1-to-4
Mouse mm9 ENSMUSG00000026482 Rgl1 1-to-4
Mouse mm9 ENSMUSG00000026821 Ralgds 1-to-4
Mouse mm9 ENSMUSG00000040146 Rgl3 1-to-4
Mouse mm9 ENSMUSG00000041354 Rgl2 1-to-4
Rat rn6 ENSRNOG00000002347 Rgl1 1-to-2
Rat rn6 ENSRNOG00000013027 Rgl3 1-to-2
Cow bosTau6 ENSBTAG00000004194 RALGDS 1-to-4
Cow bosTau6 ENSBTAG00000008198 RGL3 1-to-4
Cow bosTau6 ENSBTAG00000016827 RGL2 1-to-4
Cow bosTau6 ENSBTAG00000019630 RGL1 1-to-4
Chicken galGal4 ENSGALG00000003412 1-to-2
Chicken galGal4 ENSGALG00000004728 RGL1 1-to-2
Chicken galGal3 ENSGALG00000003412 1-to-2
Chicken galGal3 ENSGALG00000004728 Q5ZIY0_CHICK 1-to-2
Zebrafish danRer10 ENSDARG00000005989 rgl1 1-to-5
Zebrafish danRer10 ENSDARG00000007727 rgl2 1-to-5
Zebrafish danRer10 ENSDARG00000022185 RGL3 (1 of 2) 1-to-5
Zebrafish danRer10 ENSDARG00000042409 RGL4 1-to-5
Zebrafish danRer10 ENSDARG00000071213 rgl3a 1-to-5