FBgn0030286 @ dm6
Biotype
protein_coding
Gene Symbol
CG1657
Description
The gene GTPase activating protein and VPS9 domains 1 is referred to in FlyBase by the symbol DmelGapvd1 (CG1657, FBgn0030286). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11325385..11334071. Its molecular function is described by: GTPase activating protein binding; guanyl-nucleotide exchange factor activity; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of protein transport; regulation of GTPase activity; signal transduction; regulation of Rab protein signal transduction. 7 alleles are reported. The phenotypes of these alleles manifest in: garland cell; slit diaphragm. The phenotypic classes of alleles include: endocytosis defective; viable; partially lethal - majority die; some die during pupal stage; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, in stages of adults of both sexes.
Coordinates
chrX:11325385-11334071:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000165219 | GAPVD1 | 1-to-1 |
| Human | hg19 | ENSG00000165219 | GAPVD1 | 1-to-1 |
| Mouse | mm10 | ENSMUSG00000026867 | Gapvd1 | 1-to-1 |
| Mouse | mm9 | ENSMUSG00000026867 | Gapvd1 | 1-to-1 |
| Rat | rn6 | ENSRNOG00000017925 | Gapvd1 | 1-to-1 |
| Cow | bosTau6 | ENSBTAG00000011544 | GAPVD1 | 1-to-1 |
| Chicken | galGal4 | ENSGALG00000000993 | GAPVD1 | 1-to-1 |
| Chicken | galGal3 | ENSGALG00000000993 | GAPVD1 | 1-to-1 |
| Zebrafish | danRer10 | ENSDARG00000090183 | gapvd1 | 1-to-1 |