FBgn0032252 @ dm6
Biotype
protein_coding
Gene Symbol
loh
Description
The gene lonely heart is referred to in FlyBase by the symbol Dmelloh (CG6232, FBgn0032252). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:10442534..10450080. Its molecular function is described by: peptidase activity. It is involved in the biological process described with: positive regulation of extracellular matrix assembly; larval heart development. 25 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval heart; embryonic/larval cardial cell; embryonic/larval pericardial cell; embryonic/larval alary muscle. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; lethal - all die before end of larval stage; short lived; cell shape defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages.
Coordinates
chr2L:10442534-10450080:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000143382 | ADAMTSL4 | 1-to-2 |
| Human | hg38 | ENSG00000187720 | THSD4 | 1-to-2 |
| Human | hg19 | ENSG00000143382 | ADAMTSL4 | 1-to-2 |
| Human | hg19 | ENSG00000187720 | THSD4 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000015850 | Adamtsl4 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000032289 | Thsd4 | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000015850 | Adamtsl4 | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000032289 | Thsd4 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000027742 | Adamtsl2 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000049385 | Adamtsl4 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000003604 | ADAMTSL4 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000011644 | THSD4 | 1-to-2 |
| Chicken | galGal4 | ENSGALG00000004087 | THSD4 | 1-to-1 |
| Chicken | galGal3 | ENSGALG00000004087 | THSD4 | 1-to-1 |
| Zebrafish | danRer10 | ENSDARG00000055439 | adamtsl7 | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000063407 | ADAMTSL4 | 1-to-2 |