FBgn0037659 @ dm6
Biotype
protein_coding
Gene Symbol
Kdm2
Description
The gene Lysine (K)-specific demethylase 2 is referred to in FlyBase by the symbol DmelKdm2 (CG11033, FBgn0037659). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3R:9052495..9063245. Its molecular function is described by: zinc ion binding; histone demethylase activity (H3-trimethyl-K4 specific); DNA binding; histone demethylase activity (H3-K36 specific). It is involved in the biological process described with 8 unique terms, many of which group under: anatomical structure development; regulation of protein metabolic process; negative regulation of nitrogen compound metabolic process; muscle structure development; multicellular organismal process. 51 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; nucleolus. The phenotypic classes of alleles include: lethal; phenotype; lethal - all die before end of P-stage; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.
Coordinates
chr3R:9052495-9063245:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000089094 | KDM2B | 1-to-3 |
Human | hg38 | ENSG00000099364 | FBXL19 | 1-to-3 |
Human | hg38 | ENSG00000173120 | KDM2A | 1-to-3 |
Human | hg19 | ENSG00000089094 | KDM2B | 1-to-3 |
Human | hg19 | ENSG00000099364 | FBXL19 | 1-to-3 |
Human | hg19 | ENSG00000173120 | KDM2A | 1-to-3 |
Mouse | mm10 | ENSMUSG00000029475 | Kdm2b | 1-to-3 |
Mouse | mm10 | ENSMUSG00000030811 | Fbxl19 | 1-to-3 |
Mouse | mm10 | ENSMUSG00000054611 | Kdm2a | 1-to-3 |
Mouse | mm9 | ENSMUSG00000029475 | Kdm2b | 1-to-3 |
Mouse | mm9 | ENSMUSG00000030811 | Fbxl19 | 1-to-3 |
Mouse | mm9 | ENSMUSG00000054611 | Kdm2a | 1-to-3 |
Rat | rn6 | ENSRNOG00000018986 | Fbxl19 | 1-to-3 |
Rat | rn6 | ENSRNOG00000019145 | Kdm2a | 1-to-3 |
Rat | rn6 | ENSRNOG00000025702 | Kdm2b | 1-to-3 |
Cow | bosTau6 | ENSBTAG00000002328 | KDM2B | 1-to-3 |
Cow | bosTau6 | ENSBTAG00000040555 | FBXL19 | 1-to-3 |
Cow | bosTau6 | ENSBTAG00000044032 | KDM2A | 1-to-3 |
Chicken | galGal4 | ENSGALG00000004225 | KDM2B | 1-to-2 |
Chicken | galGal3 | ENSGALG00000004225 | KDM2B | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000036593 | kdm2ba | 1-to-6 |
Zebrafish | danRer10 | ENSDARG00000046010 | kdm2bb | 1-to-6 |
Zebrafish | danRer10 | ENSDARG00000059653 | kdm2aa | 1-to-6 |
Zebrafish | danRer10 | ENSDARG00000100575 | KDM2B (2 of 2) | 1-to-6 |
Zebrafish | danRer10 | ENSDARG00000103362 | FBXL19 | 1-to-6 |