FBgn0041585 @ dm6
Biotype
protein_coding
Gene Symbol
olf186-F
Description
The gene Orai is referred to in FlyBase by the symbol DmelOrai (CG11430, FBgn0041585). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 2R:17843442..17860582. Its molecular function is described by: calcium channel regulator activity; store-operated calcium channel activity; calcium channel activity. It is involved in the biological process described with: nervous system development; calcium ion transmembrane transport; positive regulation of calcineurin-NFAT signaling cascade; store-operated calcium entry; positive regulation of calcium ion transport. 37 alleles are reported. The phenotypes of these alleles manifest in: neuron projection; adult segment; plasma membrane bounded cell projection; cell projection; appendage. The phenotypic classes of alleles include: visible; phenotype; increased mortality; flight defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:17843442-17860582:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000160991 | ORAI2 | 1-to-3 |
| Human | hg38 | ENSG00000175938 | ORAI3 | 1-to-3 |
| Human | hg38 | ENSG00000276045 | ORAI1 | 1-to-3 |
| Human | hg19 | ENSG00000160991 | ORAI2 | 1-to-3 |
| Human | hg19 | ENSG00000175938 | ORAI3 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000039747 | Orai2 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000043964 | Orai3 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000049686 | Orai1 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000039747 | Orai2 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000043964 | Orai3 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000049686 | Orai1 | 1-to-3 |
| Rat | rn6 | ENSRNOG00000001336 | Orai1 | 1-to-3 |
| Rat | rn6 | ENSRNOG00000001427 | Orai2 | 1-to-3 |
| Rat | rn6 | ENSRNOG00000039730 | Orai3 | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000002344 | ORAI3 | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000004457 | ORAI1 | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000012050 | ORAI2 | 1-to-3 |
| Chicken | galGal4 | ENSGALG00000001837 | ORAI2 | 1-to-2 |
| Chicken | galGal4 | ENSGALG00000004240 | ORAI1 | 1-to-2 |
| Chicken | galGal3 | ENSGALG00000001837 | ORAI2_CHICK | 1-to-2 |
| Chicken | galGal3 | ENSGALG00000004240 | ORAI1 | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000004154 | orai1b | 1-to-3 |
| Zebrafish | danRer10 | ENSDARG00000011515 | orai1a | 1-to-3 |
| Zebrafish | danRer10 | ENSDARG00000035148 | orai2 | 1-to-3 |