FBgn0260959 @ dm6
Biotype
protein_coding
Gene Symbol
MCPH1
Description
The gene Microcephalin is referred to in FlyBase by the symbol DmelMCPH1 (CG42572, FBgn0260959). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2R:11895997..11903918. Its molecular function is described by: . It is involved in the biological process described with: pole cell formation; mushroom body development; mitotic cell cycle; mitotic cell cycle, embryonic. 21 alleles are reported. The phenotypes of these alleles manifest in: spindle; centrosome; primordial germ cell; eye; adult mushroom body. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult male stages.
Coordinates
chr2R:11895997-11903918:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000147316 | MCPH1 | 1-to-1 |
| Human | hg19 | ENSG00000147316 | MCPH1 | 1-to-1 |
| Mouse | mm10 | ENSMUSG00000039842 | Mcph1 | 1-to-1 |
| Mouse | mm9 | ENSMUSG00000039842 | Mcph1 | 1-to-1 |
| Rat | rn6 | ENSRNOG00000028586 | Mcph1 | 1-to-1 |
| Cow | bosTau6 | ENSBTAG00000011032 | MCPH1 | 1-to-1 |
| Chicken | galGal4 | ENSGALG00000016332 | MCPH1 | 1-to-1 |
| Chicken | galGal3 | ENSGALG00000016332 | MCPH1 | 1-to-1 |
| Zebrafish | danRer10 | ENSDARG00000058372 | mcph1 | 1-to-1 |