FBgn0264089 @ dm6
Biotype
protein_coding
Gene Symbol
sli
Description
The gene slit is referred to in FlyBase by the symbol Dmelsli (CG43758, FBgn0264089). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 2R:15869495..15922118. Its molecular function is described by: Roundabout binding; heparin binding; calcium ion binding. It is involved in the biological process described with 21 unique terms, many of which group under: embryo development; positive regulation of cell motility; positive regulation of cell adhesion; positive regulation of response to external stimulus; exocrine system development. 79 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; segmental subdivision of organ system; cell projection; larval multidendritic neuron; neuron projection. The phenotypic classes of alleles include: lethal - all die before end of prepupal stage; phenotype; cell shape defective; increased mortality during development.
Coordinates
chr2R:15869495-15922118:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000145147 | SLIT2 | 1-to-3 |
| Human | hg38 | ENSG00000184347 | SLIT3 | 1-to-3 |
| Human | hg38 | ENSG00000187122 | SLIT1 | 1-to-3 |
| Human | hg19 | ENSG00000145147 | SLIT2 | 1-to-3 |
| Human | hg19 | ENSG00000184347 | SLIT3 | 1-to-3 |
| Human | hg19 | ENSG00000187122 | SLIT1 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000025020 | Slit1 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000031558 | Slit2 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000056427 | Slit3 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000025020 | Slit1 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000031558 | Slit2 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000056427 | Slit3 | 1-to-3 |
| Rat | rn6 | ENSRNOG00000004356 | Lrrc52 | 1-to-16 |
| Rat | rn6 | ENSRNOG00000007377 | Slit3 | 1-to-16 |
| Rat | rn6 | ENSRNOG00000009649 | Slitrk5 | 1-to-16 |
| Rat | rn6 | ENSRNOG00000009821 | Slitrk3 | 1-to-16 |
| Rat | rn6 | ENSRNOG00000026065 | Slit1 | 1-to-16 |
| Cow | bosTau6 | ENSBTAG00000005108 | SLIT2 | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000017746 | SLIT3 | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000043991 | SLIT1 | 1-to-3 |
| Chicken | galGal4 | ENSGALG00000001916 | SLIT3 | 1-to-3 |
| Chicken | galGal3 | ENSGALG00000001916 | Q90Z43_CHICK | 1-to-3 |
| Zebrafish | danRer10 | ENSDARG00000004246 | slit2 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000034268 | slit3 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000044954 | slit1a | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000099446 | slit1b | 1-to-4 |