BtaEX0007958 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000018367 | CD6
Description
CD6 molecule [Source:HGNC Symbol;Acc:HGNC:1691]
Coordinates
chr29:37926736-37929496:+
Coord C1 exon
chr29:37926736-37927047
Coord A exon
chr29:37927652-37927954
Coord C2 exon
chr29:37929431-37929496
Length
303 bp
Sequences
Splice sites
3' ss Seq
ACCCCCCGCACCCCCTGCAGAGC
3' ss Score
9.5
5' ss Seq
CAGGTACCC
5' ss Score
8.63
Exon sequences
Seq C1 exon
ATAAACGCGATTTGAAATTGGTGGGTGGTGGCAGCCCATGTGAGGGCCGCGTGGAGATGCTGGAGCACGGCCAGTGGGGTTCGGTGTGTGACGACACATGGGACCTGGAGGATGCTCACGTGGTGTGCCGGCAGCTGGGCTGCGGCTGGGCCGTCCAGGCCCTGCCCGGCTTGCACTTTGCCCCTGGCCAAGGACGCATCCACTGGGACCAAGTGAACTGCACCGGGTTGGAGACCTACCTGTGGCACTGCCCGGGGCTGCCCGGAAATGGGTACTGTGGCCACAAGGAGGATGCCGGAGTGGTGTGTTCAG
Seq A exon
AGCACCAGTCCTGGCGCCTGACCGGGGGCACTGACCCCTGTGAGGGGCAGGTGGAGGTGTACTTCCGAGGGGTCTGGAACACAGTGTGTGACAGTGAGTGGTACGACTCAGAGGCCAACGTGCTCTGCCAGGACTTGGGCTGTGGGACCGTGGCCCGGGTGCCCAAGGGGCTGCCCCACTCCTTGTCGGGCAAGATGTTCTACTCATGCAAGGGAAAGGAGTCCACCCTCTCCAAATGCTTCTGGCGGTTCAACAACTCCAACCTCTGCAGACAGTCCCAGGCAGCCAGGGTCCTCTGCTCAG
Seq C2 exon
GTGCCCGGAGTCTGCTCAATCTGTCCATTACTGAAGTCCCTGCAAGTGGTCAGCCGGTCACTGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000018367_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0053013=SRCR=WD(100=92.4)
A:
PF0053013=SRCR=WD(100=92.2)
C2:
PF151021=TMEM154=PU(22.8=91.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGAAATTGGTGGGTGGTGGC
R:
GACCACTTGCAGGGACTTCAG
Band lengths:
352-655
Functional annotations
There are 1 annotated functions for this event
PMID: 17371992
Exon 5 skipping (CD6Deltad3) in the third SRCR (scavenger receptor cysteine-rich) domain causes a failure to localize in the immunological synapse and bind CD166.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development