GgaEX1002176 @ galGal4
Exon Skipping
Description
Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:H9KZK0]
Coordinates
chrLGE64:612929-656501:-
Coord C1 exon
chrLGE64:656172-656501
Coord A exon
chrLGE64:621352-621681
Coord C2 exon
chrLGE64:612929-613255
Length
330 bp
Sequences
Splice sites
3' ss Seq
ACACTCATAAATTTTTGCAGACT
3' ss Score
6.4
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
GGGCACCTGCTCCAGGTGAGATCCAGGTCAGGCTGATAAACGGCTCAAGCTCTTGCTCTGGCAGAGTGGAAATCTTCCACAATGGCAGCTGGGGCACGGTGTGTGATGATGGCTGGAATATGGCGGCTGCTGAAGTGGTGTGCAGAGAAATGGGCTGTGGCTCAGCTCTGTCAGCCCCCGTTGGGGCTACTTTTGGGCAAGGGGCAGGACAAATTTGGATGGATGATGTGACCTGTGCTGGGACGGAGGCTGCCCTTTCTCTGTGCCAGGTCAGTTCCTGGGGAAGCCACAATTGTGGCCACAGAGAGGATGCTGGTGTTGAATGCTCAG
Seq A exon
ACTCGATCATCCCAGAGCCTGCTCATCTCCGACTGGTGAACGGCTCACACCGCTGTGCTGGCCGAGTTGAGGTGTTTCACAAGGAGATGTGGGGAGCTGTGTGCGACCATGGCTGGGATAAAATGGATGCGGAGGTTGTGTGCCGGCAGCTGGGCTGTGGGACAGCACTGTCGGCCTCAGGTGAAGCACACTTGGATGCTGCATCTCTTCGTGTGTGGTTGGACAATGTGAGCTGCGAGGGAACAGAACTCTCTCTTACAAAATGCAGAGCGAGCCCATGGGGAAAGAGCAGCTGCAGCCATGGAAAGCATGCTAGTGTTGTGTGCTCAG
Seq C2 exon
CGTTGTCAGATGACACATCAACTCTTCGCCTGGTGAATGGCCCACATCGCTGTTCTGGTAGAGTCGAGGTGTTTCACAATCAGCAATGGGGAACTGTCTGCGATGATGGCTGGGACATGAATGATGCCATGGTGGTGTGCAACCAGTTGGGCTGTGGGGAAGCACTGTCAGCCACAACACAAGCTTCATTTGGTCGAGGGGCGGATCCCATCTGGCTGGACAGAGTTGCTTGCACTGGGAGAGAAAACACTCTCATACAGTGCAGGGCCAGACCCTGGGGAGTCAACGTCTGCACACATGAAGAAGATGCTGGTGTTGTGTGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000009103_MULTIEX1-16/22=C1-21
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0053013=SRCR=WD(100=88.3)
A:
PF0053013=SRCR=WD(100=88.3)
C2:
PF0053013=SRCR=WD(100=91.6)
Main Inclusion Isoform:
ENSGALT00000014816fB4040
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
- GgaALTA1001230-1/4
- GgaALTA1001230-4/4
- GgaEX1002169
- GgaEX1002170
- GgaEX1002171
- GgaEX1002172
- GgaEX1002173
- GgaEX1002174
- GgaEX1002175
- GgaEX1002177
- GgaEX1002178
- GgaEX1002179
- GgaEX1002180
- GgaEX1002181
- GgaEX1002182
- GgaEX1002184
- GgaEX1002185
- GgaEX1002186
- GgaEX1002187
- GgaEX1002188
- GgaEX1002189
- GgaEX1002190
- GgaEX7012057
- GgaINT1001353
- GgaINT1001359
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGATGTGACCTGTGCTGGG
R:
CAGTGCAAGCAACTCTGTCCA
Band lengths:
346-676
Functional annotations
There are 1 annotated functions for this event
PMID: 17371992
Exon 5 skipping (CD6Deltad3) in the third SRCR (scavenger receptor cysteine-rich) domain causes a failure to localize in the immunological synapse and bind CD166.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]