BtaEX0009092 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000012274 | CIZ1
Description
CDKN1A interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:16744]
Coordinates
chr11:98819125-98823001:-
Coord C1 exon
chr11:98822886-98823001
Coord A exon
chr11:98821351-98821422
Coord C2 exon
chr11:98819125-98819354
Length
72 bp
Sequences
Splice sites
3' ss Seq
GCCAAATTGCTTTCTCAAAGGAC
3' ss Score
4.87
5' ss Seq
TGGGTATTA
5' ss Score
1.91
Exon sequences
Seq C1 exon
GGGGCTCCCCCAGCAGCAGCCACAGCAGCAGCTCCTGACTCTCCAGGGGACCAGCCCCACCTCCCTCCTCAACGGCTCTGTGCTGCAGAGAGCTTTGCTTCTGCAGCAGTTACAAG
Seq A exon
GACTGGACCAATTTGCAATGCCACCAGCCACGTATGACAGTGCCAGTTTCACCATGCCCACGGCAACACTGG
Seq C2 exon
GTAACCTCCGTGGCTACAACCTGGCCACCCCCAACCTGACACCCCCCAGCCTCACACCTCCACAGCTGGCCACCCCAAATCTCCAGCAATTCTTTCCTCAGGCCACTCGGCAGTCCCTGCTGGGTCCTCCTCCCGTTGGGGTCCCCATCAACCCCTCCCAGCTCAACCTTTCAGGGCGAACCCCCCAGAAACAGACTCGGACCTCCTCCTCTACGACCCCCAATCGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000012274_MULTIEX2-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
NA
No structure available
Features
Disorder rate (Iupred):
C1=0.489 A=NA C2=0.996
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCAGCTCCTGACTCTCCAG
R:
ATTGCTGGAGATTTGGGGTGG
Band lengths:
180-252
Functional annotations
There are 1 annotated functions for this event
PMID: 32249828
[CRISPR screen]. This alternative exon is implicated in cell fitness by a CRISPR-based exon deletion phenotypic screen in RPE-1 cells.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development