BtaEX6070125 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000009924 | MR1
Description
Bos taurus major histocompatibility complex, class I-related (MR1), mRNA. [Source:RefSeq mRNA;Acc:NM_001190298]
Coordinates
chr16:63655127-63659861:+
Coord C1 exon
chr16:63655127-63655402
Coord A exon
chr16:63656009-63656110
Coord C2 exon
chr16:63659803-63659861
Length
102 bp
Sequences
Splice sites
3' ss Seq
CCTTATTTGCTTACTTTCAGAAT
3' ss Score
9.46
5' ss Seq
GAGGTAAGA
5' ss Score
10.06
Exon sequences
Seq C1 exon
AGCCCCCCAAAGTCAGAGTCAATCACAAAGAAACTTTCCCAGGGATTACAACTCTTTACTGCAGAGCTTATGGCTTTTACCCCCCAGAAATTTCCATTAACTGGATGAAAAACGGGGAAGAAATTTTCCAAGATACCGATTATGGAGGCATTCTTCCCAGTGGGGATGGGACCTATCAGACTTGGGTGTCTGTTGAGCTGGATCCTCAGAATGGTGACATTTACTCCTGTCACGTGGAGCATGGCGGAGTCCACATGGTTCTTCAGGGTTTCCAGG
Seq A exon
AATCGGAAACTATACTTCTCGTGGTGAAAGCTGTTGGGTTCATTGTCCTCGCCATTGCCCTGGCTGGAGTTGGCATCCTAGCCTGGCGAAAGAGGCCCCGAG
Seq C2 exon
GGAAAAACAAAGTCATCTGCCTTTCTACACCAGAACACTGATGGGAGATGGCTGCTTTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000009924-'9-6,'9-5,10-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.027 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0765410=C1-set=WD(100=89.2)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCCAGAAATTTCCATTAACTG
R:
AAGCAGCCATCTCCCATCAGT
Band lengths:
253-355
Functional annotations
There are 1 annotated functions for this event
PMID: 32963314
[Negative results]. Expression of pCI:MR1CRFP (skipping of HsaEX0040046 and HsaEX0040047) pre or post induction of MR1A expression did not impact MR1A-mediated expression or antigen presentation, indicating this was not a general consequence of transfection.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]