MmuEX6028381 @ mm9
Exon Skipping
Gene
ENSMUSG00000026471 | Mr1
Description
major histocompatibility complex, class I-related [Source:MGI Symbol;Acc:MGI:1195463]
Coordinates
chr1:156975008-156979765:-
Coord C1 exon
chr1:156979490-156979765
Coord A exon
chr1:156977763-156977861
Coord C2 exon
chr1:156975008-156976455
Length
99 bp
Sequences
Splice sites
3' ss Seq
TTTTTCTCATTTACTTACAGAAT
3' ss Score
9.99
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
Exon sequences
Seq C1 exon
AGCATCCAGTGGTAAGAACAACTCGAAAGGAAACTTTTCCAGGGATTACAACTTTCTTCTGCAGAGCTCATGGCTTCTACCCACCAGAAATTTCCATGACATGGATGAAAAATGGGGAAGAAATTGCCCAAGAAGTGGATTACGGAGGGGTACTTCCCAGCGGGGATGGAACCTATCAAACGTGGCTGTCAGTTAATCTGGATCCTCAGAGCAATGATGTTTATTCTTGTCATGTGGAGCACTGTGGTCGCCAAATGGTTCTGGAGGCCCCTCGGG
Seq A exon
AATCAGGGGACATCCTTCGAGTGAGCACGATCTCTGGAACCACAATTCTCATCATCGCCCTGGCTGGAGTTGGTGTTCTGATCTGGAGAAGGTCACAAG
Seq C2 exon
AACTAAAAGAAGTCATGTACCAACCCACCCAAGTGAATGAGGGAAGCTCTCCCTCTTAGGAGCCACAATCTCTGCTCTCAGGCATCCGCATGTCTTGGCCATACTCCTGATGCAACCGGGGACTGTAAAACTGAGCACTTGTGACAGGAAGATAGGAGCTACAAATTTTTCTTCATTCTTTGGCTCCAGAAGAGCTGTCAACTTTTAGGCTCTTGATAGACTCCTTTATCACAGTCAACTTTAAATATAGTTTGTCTCATGACCCAATACTTCCCAATATTGTAGTTCTCAATAGTGATTTACAAGTAGATCACAGAGTATCAGAGCCGCAAGCAACTTTCTCACCTAAGCAGGAGATGTCTTCTAAAATGTCATAGACTTGAGCATTAGCCTTCACTCAACATTATGTGCAAGTTCCCCCATTCTACTACAAAACAGCCTTTCTTGTTCATTTTCTCTCCTGAGAATGTTTACCATGTAAGAACTTTGACCACTATGGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026471-'5-5,'5-4,6-5=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.065 A=0.000 C2=0.684
Domain overlap (PFAM):
C1:
PF0765410=C1-set=WD(100=89.2)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTGGTCGCCAAATGGTTCT
R:
GCTCAGTTTTACAGTCCCCGG
Band lengths:
171-270
Functional annotations
There are 1 annotated functions for this event
PMID: 32963314
[Negative results]. Expression of pCI:MR1CRFP (skipping of HsaEX0040046 and HsaEX0040047) pre or post induction of MR1A expression did not impact MR1A-mediated expression or antigen presentation, indicating this was not a general consequence of transfection.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: