RnoEX0055527 @ rn6
Exon Skipping
Gene
ENSRNOG00000003522 | Mr1
Description
major histocompatibility complex, class I-related [Source:RGD Symbol;Acc:1593291]
Coordinates
chr13:72771984-72774835:-
Coord C1 exon
chr13:72774714-72774835
Coord A exon
chr13:72773739-72773843
Coord C2 exon
chr13:72771984-72772473
Length
105 bp
Sequences
Splice sites
3' ss Seq
TGTTTCTCATTTCCTTACAGAAT
3' ss Score
10.78
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
Exon sequences
Seq C1 exon
TTCAGAAGAAGGCATCGGATCCCTTGGAGCTGGAGTTACGGATGCTTGTGAACTATCCCAGTTCCCCCATAAGAGCAGTCAGTGCTCTTAAGGGGCTGAGCCATTTCTCCAGTTCCAACAAG
Seq A exon
AATCAGGAAACACCCTTCTAGTGGCAAACACGATCTCTGGGACCATAATTCTCATCATTGTCCTGGCTGGAGTTGGTGCCCTGATCTGGAGAAGAAGGTCACGAG
Seq C2 exon
AACCAAAAGAAGTCATGTACCAACCCACCCAAGTCAATGAGGGCAGCTCTCCCTCTTAGGAGCCATGGTCTCTGCTCTCAGGCACCCACGTGTCTCAGCCAAACTCCTGACACGGGATTGTAGAATTGAGCATTTGTGACAAGAAGATAAGAGCTACAAATTTGTCTTCGTTCTTTGGCTCCAGAAGAACTGTCAATTTTTAGGCTCTTGATAGACTTAAAACATAGTTTGTCTCATGACCCAATACCTCCCAATATTATATTTCTCAATGGTGATAGATTAGAGTCTCAGAGCAGCAAGCAGCTTTCTCATCCAAGATGTTTTCTAAAATGTCACAGACTTGGCTCTTTTCTCTGCTCTCTTACCCTCTTCAACCTTTATCCCTTTTCTCCCCATTCCCTATCCCCCTTCCCTCCCGTGCTCATGGCTGGCCTTTACTTCTCCCCTCTTCTACTTTTCTCTCATTAAACCTTTCCACGTGGAAAAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000003522-'11-10,'11-9,12-10
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.024 A=0.119 C2=0.789
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENSRNOT00000004694fB8930
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCCAGTTCCCCCATAAGAGC
R:
TGGAGCCAAAGAACGAAGACA
Band lengths:
250-355
Functional annotations
There are 1 annotated functions for this event
PMID: 32963314
[Negative results]. Expression of pCI:MR1CRFP (skipping of HsaEX0040046 and HsaEX0040047) pre or post induction of MR1A expression did not impact MR1A-mediated expression or antigen presentation, indicating this was not a general consequence of transfection.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]