BtaEX6091685 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000039483 | DSG3
Description
Bos taurus desmoglein 3 (DSG3), mRNA. [Source:RefSeq mRNA;Acc:NM_001192685]
Coordinates
chr24:25978319-25983881:-
Coord C1 exon
chr24:25983818-25983881
Coord A exon
chr24:25981322-25981569
Coord C2 exon
chr24:25978319-25979721
Length
248 bp
Sequences
Splice sites
3' ss Seq
CACTTTATCCCTGTTTTTAGAAG
3' ss Score
7.4
5' ss Seq
CAGGTAATC
5' ss Score
6.99
Exon sequences
Seq C1 exon
GAAATCACAAATATCGGTGTGCCACCTATAACTGCCAATGGAGTTGATTTCATGGAAAATTCTG
Seq A exon
AAGTCTGTACAAATACATATGCTGGAGGGACGGTGGTAGAAGGAGCTTCGGGAATGGAACTGACCACCAATCTTGGAGCAGCTGCAGGATCTGGGGGTGCCGCGGGGTTCGGAGCAACCGCCGGTCTGAGCAACTTTTCCGTGGGACAGTCCGGGACGATGAGAACAAGGCATTCCACCGGAGGAACCAACAAGGACTTTGGGGAAGGGGCAATAAACATGAAATTCCTGGACTCCTACTTTTCTCAG
Seq C2 exon
AAAGCATTTGCCTGTGCAGATGAAGACGACAGCCAGGAAGCAAATGACTGCTTGCTGGTCTATGATAATGAAGGAATCGAGGCCCCCAGTTCTCCCGTCGGCTCCCTGGGTTGTTGCAGTTTTATTGCCGATGATTTTGACGAGAGTTTCTTGGACTCCCTCGGCCCCAAATTTAAAAAGCTGGCCGAGATAAGCCTCGGGATGGATGACGAAACCAAAAGCTCTCAGCCGCCTACCAAAGACAGCAGTTCTAGGGTTGACGCCTGTGGCCAACACGTACAAGTCCAGCAGTCAGAGTCTGTTAGGTACCAGACTTTGTCAGGCAGCCAGGGGGCATCTGCGCTGTCTGCTTCCAGTTCTGTCCTGCAGCCCGCCGTTTCCATCACTGACCCTTTGCAGCATGGTAGCTATCTGGTAACGGAGACTTACTCGGCTTCTTCTGGTTCCCTTGTGCAACCTCCCGCTGCCGTTTTTGATCCACTTCTCACGCAAAATGTGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000039483-'13-16,'13-14,14-16=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.273 A=0.193 C2=0.223
Domain overlap (PFAM):
C1:
NO
A:
PF0104912=Cadherin_C=PU(12.8=12.0)
C2:
PF0104912=Cadherin_C=PD(84.6=31.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTGCCACCTATAACTGCCA
R:
AACTGCTGTCTTTGGTAGGCG
Band lengths:
298-546
Functional annotations
There are 1 annotated functions for this event
PMID: 11500511
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: cleavage reaction, confocal microscopy, edman degradation, western blot. ELM ID: ELMI001926; ELM sequence: DYADG; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]