RnoEX6058253 @ rn6
Exon Skipping
Gene
ENSRNOG00000016632 | Dsg3
Description
desmoglein 3 [Source:RGD Symbol;Acc:1592103]
Coordinates
chr18:15650526-15658106:-
Coord C1 exon
chr18:15658043-15658106
Coord A exon
chr18:15655485-15655702
Coord C2 exon
chr18:15650526-15654423
Length
218 bp
Sequences
Splice sites
3' ss Seq
TCTCTCTCTCCTGTCTTTAGAAG
3' ss Score
9.7
5' ss Seq
CAGGTAGCA
5' ss Score
6.37
Exon sequences
Seq C1 exon
GAAATCACAAATATTTGTGTTCCTCCAGTCACAAGCAATGGAGCAGATTTTATGGAAAGTTCTG
Seq A exon
AAGTTTGCACAAATACCTACGCTGGAGGGACCCTAGTAGAAGGTGCTTCCGGAATGGAGATGACTACCAAGCTAGGAGGAGCTACGGGATCAGGAGCTGCAGTGGCGCTTGGCTTGGGTCATTCAGGAACGATGAGAACGAGGCATTCCACTGGAGGGACCTTGAAGGATTATGCTGCACCAGTGAACATGACTTTCCTAGGATCCTACTTCTCTCAG
Seq C2 exon
AAATCATCCGCCTATGCTGAGGAAGAGGATGATCGTGAAGTGAATGACTGTTTGCTGATCTACGATGACGAAGGCGAGGATGCTGCCCCCCGTTCCCCAGCCCTCAGCTCCTGCAGCTTTATGGCCGATGACCTGGACGACAGTTTCTTGGACTCCCTTGGCCCCAAATTTAAAAAGCTTGCAGAGATATGTCTTGGCGTTGATGACGAAGCCAAGCAAGTAAAGCCAGGCCCTAAAGACAGTAGTTCTGGGGCTGACGCCTGTGCTCGCCCTACAGAAGCCCTTCAGGCAGGTTCTAACAGGTACCAGACTTTGCCTGGCAGTCTAGAAGTCACTCAGTCGGGTTCTAGCAGGTACCAGACTTTGCCTGGCGGTCTGGAAGTCACTCAATCGGGTTCTAACAGGTACCAGACTTTGCCTGGCGGTCTGGAAGTTACCCAGTCGGGTTCTAACAGGTACCAGACTTTGCCTGGCGGTCTGGAAGTCACCCAATCAGGTTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000016632-'15-14,'15-13,16-14=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.227 A=0.178 C2=0.443
Domain overlap (PFAM):
C1:
NO
A:
PF0104912=Cadherin_C=PU(24.4=30.1)
C2:
PF0104912=Cadherin_C=PD(73.3=24.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAGTCACAAGCAATGGAGC
R:
CGTCAGCCCCAGAACTACTGT
Band lengths:
300-518
Functional annotations
There are 1 annotated functions for this event
PMID: 11500511
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: cleavage reaction, confocal microscopy, edman degradation, western blot. ELM ID: ELMI001926; ELM sequence: DYADG; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]