Special

DmeALTA0004941-2/2 @ dm6

Alternative 3'ss

Gene
Description
The gene Darkener of apricot is referred to in FlyBase by the symbol DmelDoa (CG42320, FBgn0265998). It is a protein_coding_gene from Dmel. It has 16 annotated transcripts and 16 polypeptides (11 unique). Gene sequence location is 3R:28888073..28922772. Its molecular function is described by: kinase activity; ATP binding; protein kinase activity; protein serine/threonine kinase activity. It is involved in the biological process described with 14 unique terms, many of which group under: multicellular organism development; visual system development; negative regulation of biological process; positive regulation of immune system process; embryo development. 88 alleles are reported. The phenotypes of these alleles manifest in: intracellular organelle; cellular anatomical entity; interommatidial bristle; sex comb; extracellular matrix. The phenotypic classes of alleles include: phenotype; increased mortality; stress response defective; increased mortality during development.
Coordinates
chr3R:28921156-28921544:+
Coord C1 exon
chr3R:28921156-28921269
Coord A exon
chr3R:28921341-28921358
Coord C2 exon
chr3R:28921359-28921544
Length
18 bp
Sequences
Splice sites
5' ss Seq
ACGGTAATA
5' ss Score
6.25
3' ss Seq
CGAAATCGTTTAACGTGTAGCAA
3' ss Score
1.6
Exon sequences
Seq C1 exon
GTGCATCTTGTTCGAACTGTATCTGGGAATCACGCTCTTCCAAACGCACGACAATCGCGAACACTTGGCCATGATGGAGCGAATCTTGGGACAAATACCATATCGCATGGCACG
Seq A exon
CAATCATACTCTTTATAG
Seq C2 exon
CAAAACCAAAACAAAGTACTTCTATCATGGTAAGTTAGATTGGGATGAGAAGTCCAGTGCGGGTCGCTACGTCCGTGATCACTGCAAGCCGTTGTTCCTGTGCCAGCTGAGCGACAGCGAGGACCACTGTGAGCTCTTCAGTCTGATCAAGAAGATGCTGGAGTACGAGCCGTCGTCACGCATCAC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0265998-46-40,46-39-2/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact

Protein isoform when splice site is used (No Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):

C1:
PF0006920=Pkinase=FE(12.1=100)
A:
NA
C2:
PF0006920=Pkinase=FE(20.3=100)


Main Inclusion Isoform:
FBpp0289029


Main Skipping Isoform:
FBpp0289022


Other Inclusion Isoforms:
FBpp0289021, FBpp0289025, FBpp0300822, FBpp0300823, FBpp0300824


Other Skipping Isoforms:
FBpp0289020, FBpp0289023, FBpp0289026, FBpp0289027, FBpp0289028, FBpp0289030, FBpp0289031, FBpp0307567
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAACACTTGGCCATGATGGA
R:
GCACTGGACTTCTCATCCCAA
Band lengths:
117-135
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)